The enteric pathogen Cryptosporidium parvum exports proteins into the cytosol of the infected host cell

The enteric pathogen Cryptosporidium parvum exports proteins into the cytosol of the infected host cell

The parasite Cryptosporidium is responsible for diarrheal disease in young children causing death, malnutrition, and growth delay. Cryptosporidium invades enterocytes where it develops in a unique intracellular niche. Infected cells exhibit profound changes in morphology, physiology, and transcripti...

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Bibliographic Details
Main Authors: Jennifer E Dumaine, Adam Sateriale, Alexis R Gibson, Amita G Reddy, Jodi A Gullicksrud, Emma N Hunter, Joseph T Clark, Boris Striepen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-12-01
Series:eLife
Subjects:
Cryptosporidium
protein export
effector
host-pathogen interactions
Online Access:https://elifesciences.org/articles/70451

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