Evaluation of SARS-CoV-2 with a biophysical perspective

This paper intends to contribute to the collaborative efforts of the scientific community by providing a literature review of the status of the coronavirus research by adding a multi-disciplinary perspective and looking into a broad spectrum of SARS-CoV-2 studies on virus molecular structure, biophy...

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Main Authors: Sait Berk Barlas, Nur Adalier, Omer Dasdag, Suleyman Dasdag
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
Online Access:http://dx.doi.org/10.1080/13102818.2021.1885997
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author Sait Berk Barlas
Nur Adalier
Omer Dasdag
Suleyman Dasdag
author_facet Sait Berk Barlas
Nur Adalier
Omer Dasdag
Suleyman Dasdag
author_sort Sait Berk Barlas
collection DOAJ
description This paper intends to contribute to the collaborative efforts of the scientific community by providing a literature review of the status of the coronavirus research by adding a multi-disciplinary perspective and looking into a broad spectrum of SARS-CoV-2 studies on virus molecular structure, biophysical approach, electrostatic interaction and UVC rays. The paper identifies future research directions for each group of studies and points out remaining questions on the way related to COVID-19. The summary of the literature review will intend to assist future studies; provide a biophysical understanding of the virus interaction with host cells and help better identify antiviral therapy and the development of new vaccines/drugs to tackle COVID-19 and any virus outbreak. In addition to the electrostatic interactions of SARS-CoV-2, this paper also discusses whether UVC rays are a safe alternative to many chemical sterilization methods which are frequently used in our daily life since the beginning of the COVID-19 outbreak and whose health effects are controversial. This article also briefly discusses the relationship of some trace elements with COVID-19 infection. In conclusion, focusing on biophysical mechanisms of virus–cell interactions with a broad perspective has potential to give a different approach to the reader for future treatment methods.
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spelling doaj.art-ae46583c1065458ab8f4f431a5f445962022-12-21T20:22:15ZengTaylor & Francis GroupBiotechnology & Biotechnological Equipment1310-28181314-35302021-01-0135139240610.1080/13102818.2021.18859971885997Evaluation of SARS-CoV-2 with a biophysical perspectiveSait Berk Barlas0Nur Adalier1Omer Dasdag2Suleyman Dasdag3Pre-Graduate Internship Department, Medical School, Koc UniversityPre-Graduate Internship Department, Medical School, Koc UniversityPre-Graduate Internship Department, Medical School, Biruni UniversityBiophysics Department, Medical School, Istanbul Medeniyet UniversityThis paper intends to contribute to the collaborative efforts of the scientific community by providing a literature review of the status of the coronavirus research by adding a multi-disciplinary perspective and looking into a broad spectrum of SARS-CoV-2 studies on virus molecular structure, biophysical approach, electrostatic interaction and UVC rays. The paper identifies future research directions for each group of studies and points out remaining questions on the way related to COVID-19. The summary of the literature review will intend to assist future studies; provide a biophysical understanding of the virus interaction with host cells and help better identify antiviral therapy and the development of new vaccines/drugs to tackle COVID-19 and any virus outbreak. In addition to the electrostatic interactions of SARS-CoV-2, this paper also discusses whether UVC rays are a safe alternative to many chemical sterilization methods which are frequently used in our daily life since the beginning of the COVID-19 outbreak and whose health effects are controversial. This article also briefly discusses the relationship of some trace elements with COVID-19 infection. In conclusion, focusing on biophysical mechanisms of virus–cell interactions with a broad perspective has potential to give a different approach to the reader for future treatment methods.http://dx.doi.org/10.1080/13102818.2021.1885997sars-cov-2biophysical perspectiveelectrostatic interactiontrace elementsuvc sterilizationcovid-19
spellingShingle Sait Berk Barlas
Nur Adalier
Omer Dasdag
Suleyman Dasdag
Evaluation of SARS-CoV-2 with a biophysical perspective
Biotechnology & Biotechnological Equipment
sars-cov-2
biophysical perspective
electrostatic interaction
trace elements
uvc sterilization
covid-19
title Evaluation of SARS-CoV-2 with a biophysical perspective
title_full Evaluation of SARS-CoV-2 with a biophysical perspective
title_fullStr Evaluation of SARS-CoV-2 with a biophysical perspective
title_full_unstemmed Evaluation of SARS-CoV-2 with a biophysical perspective
title_short Evaluation of SARS-CoV-2 with a biophysical perspective
title_sort evaluation of sars cov 2 with a biophysical perspective
topic sars-cov-2
biophysical perspective
electrostatic interaction
trace elements
uvc sterilization
covid-19
url http://dx.doi.org/10.1080/13102818.2021.1885997
work_keys_str_mv AT saitberkbarlas evaluationofsarscov2withabiophysicalperspective
AT nuradalier evaluationofsarscov2withabiophysicalperspective
AT omerdasdag evaluationofsarscov2withabiophysicalperspective
AT suleymandasdag evaluationofsarscov2withabiophysicalperspective