Serum oxidized low-density lipoprotein level as a marker of oxidative stress in patients undergoing hyperbaric oxygen therapy
Objective: Oxidative stress (OS) is involved in the pathogenesis of atherosclerosis. Hyperbaric oxygen therapy (HBOT), in which 100% oxygen is inhaled under hyperbaric pressure, may create OS. Therefore, the aim of this research was to measure the serum oxidized low-density lipoprotein (oxLDL) level...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
KARE Publishing
2017-09-01
|
| Series: | Türk Kardiyoloji Derneği Arşivi |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-28302 |
| _version_ | 1797922197575041024 |
|---|---|
| author | Kudret Keskin Hakan Kilci Gökhan Aksan Gökhan Çetinkal Süleyman Sezai Yıldız Füsun Kocaman Türk Gülsüm Bingöl |
| author_facet | Kudret Keskin Hakan Kilci Gökhan Aksan Gökhan Çetinkal Süleyman Sezai Yıldız Füsun Kocaman Türk Gülsüm Bingöl |
| author_sort | Kudret Keskin |
| collection | DOAJ |
| description | Objective: Oxidative stress (OS) is involved in the pathogenesis of atherosclerosis. Hyperbaric oxygen therapy (HBOT), in which 100% oxygen is inhaled under hyperbaric pressure, may create OS. Therefore, the aim of this research was to measure the serum oxidized low-density lipoprotein (oxLDL) level in patients undergoing HBOT.
Methods: Twenty-nine patients who underwent HBOT to treat various diseases were enrolled in this study. The serum oxLDL level was measured at the beginning of the first and after the 10th therapy session.
Results: There was no significant difference between the oxLDL level of patients before and after HBOT (4.96+-0.1 vs. 4.94+-0.1 U/mL; p=0.36).
Conclusion: HBOT seems to be safe in terms of oxLDL production up to 10 sessions. However, further large-scale studies investigating longer duration of HBOT treatment are required to understand the role of OS. |
| first_indexed | 2024-04-10T14:27:41Z |
| format | Article |
| id | doaj.art-ae4a5d1b40c84a5291de9b7bfe60d1ce |
| institution | Directory Open Access Journal |
| issn | 1016-5169 |
| language | English |
| last_indexed | 2024-04-10T14:27:41Z |
| publishDate | 2017-09-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Türk Kardiyoloji Derneği Arşivi |
| spelling | doaj.art-ae4a5d1b40c84a5291de9b7bfe60d1ce2023-02-15T16:08:59ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692017-09-0145653353710.5543/tkda.2017.28302TKDA-28302Serum oxidized low-density lipoprotein level as a marker of oxidative stress in patients undergoing hyperbaric oxygen therapyKudret Keskin0Hakan Kilci1Gökhan Aksan2Gökhan Çetinkal3Süleyman Sezai Yıldız4Füsun Kocaman Türk5Gülsüm Bingöl6Department of Cardiology, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, TurkeyDepartment of Cardiology, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, TurkeyDepartment of Cardiology, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, TurkeyDepartment of Cardiology, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, TurkeyDepartment of Cardiology, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, TurkeyHipermer Hyperbaric Oxygen Therapy Center, Undersea and Hyperbaric Medicine, İstanbul, TurkeyDepartment of Cardiology, Private İstanbul Surgery Hospital, İstanbul, TurkeyObjective: Oxidative stress (OS) is involved in the pathogenesis of atherosclerosis. Hyperbaric oxygen therapy (HBOT), in which 100% oxygen is inhaled under hyperbaric pressure, may create OS. Therefore, the aim of this research was to measure the serum oxidized low-density lipoprotein (oxLDL) level in patients undergoing HBOT. Methods: Twenty-nine patients who underwent HBOT to treat various diseases were enrolled in this study. The serum oxLDL level was measured at the beginning of the first and after the 10th therapy session. Results: There was no significant difference between the oxLDL level of patients before and after HBOT (4.96+-0.1 vs. 4.94+-0.1 U/mL; p=0.36). Conclusion: HBOT seems to be safe in terms of oxLDL production up to 10 sessions. However, further large-scale studies investigating longer duration of HBOT treatment are required to understand the role of OS.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-28302hyperbaric oxygen therapyoxidative stressoxidized low-density lipoprotein. |
| spellingShingle | Kudret Keskin Hakan Kilci Gökhan Aksan Gökhan Çetinkal Süleyman Sezai Yıldız Füsun Kocaman Türk Gülsüm Bingöl Serum oxidized low-density lipoprotein level as a marker of oxidative stress in patients undergoing hyperbaric oxygen therapy Türk Kardiyoloji Derneği Arşivi hyperbaric oxygen therapy oxidative stress oxidized low-density lipoprotein. |
| title | Serum oxidized low-density lipoprotein level as a marker of oxidative stress in patients undergoing hyperbaric oxygen therapy |
| title_full | Serum oxidized low-density lipoprotein level as a marker of oxidative stress in patients undergoing hyperbaric oxygen therapy |
| title_fullStr | Serum oxidized low-density lipoprotein level as a marker of oxidative stress in patients undergoing hyperbaric oxygen therapy |
| title_full_unstemmed | Serum oxidized low-density lipoprotein level as a marker of oxidative stress in patients undergoing hyperbaric oxygen therapy |
| title_short | Serum oxidized low-density lipoprotein level as a marker of oxidative stress in patients undergoing hyperbaric oxygen therapy |
| title_sort | serum oxidized low density lipoprotein level as a marker of oxidative stress in patients undergoing hyperbaric oxygen therapy |
| topic | hyperbaric oxygen therapy oxidative stress oxidized low-density lipoprotein. |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-28302 |
| work_keys_str_mv | AT kudretkeskin serumoxidizedlowdensitylipoproteinlevelasamarkerofoxidativestressinpatientsundergoinghyperbaricoxygentherapy AT hakankilci serumoxidizedlowdensitylipoproteinlevelasamarkerofoxidativestressinpatientsundergoinghyperbaricoxygentherapy AT gokhanaksan serumoxidizedlowdensitylipoproteinlevelasamarkerofoxidativestressinpatientsundergoinghyperbaricoxygentherapy AT gokhancetinkal serumoxidizedlowdensitylipoproteinlevelasamarkerofoxidativestressinpatientsundergoinghyperbaricoxygentherapy AT suleymansezaiyıldız serumoxidizedlowdensitylipoproteinlevelasamarkerofoxidativestressinpatientsundergoinghyperbaricoxygentherapy AT fusunkocamanturk serumoxidizedlowdensitylipoproteinlevelasamarkerofoxidativestressinpatientsundergoinghyperbaricoxygentherapy AT gulsumbingol serumoxidizedlowdensitylipoproteinlevelasamarkerofoxidativestressinpatientsundergoinghyperbaricoxygentherapy |