Cyclin-dependent Kinase 9 Induces Regional and Global Genomic DNA Methylation Via Influencing DNMT Gene Expression in Mouse Myoblast C2C12 Cells During Differentiation

Cyclin-dependent Kinase 9 Induces Regional and Global Genomic DNA Methylation Via Influencing DNMT Gene Expression in Mouse Myoblast C2C12 Cells During Differentiation

Objectives: Cyclin-dependent kinases (CDKs) including Cdk9 have been associated with cardiac differentiation. The increasing evidence has proposed that Cdk9 overexpression can regulate the epigenome. However, the current research is the first report of the Cdk9 affection on the regional and global D...

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Bibliographic Details
Main Authors: Leila Abkhooie, Mostafa Moradi Sarabi, Houman Kahroba, Hossein Ghanbarian, Soheila Montazer Saheb, Vahideh Tarhriz, Mohammad Saeid Hejazi
Format: Article
Language:English
Published: Aras Part Medical International Press 2022-01-01
Series:Crescent Journal of Medical and Biological Sciences
Subjects:
microrna
cdk9
dna methylation
gene expression
myoblast cell differentiation
Online Access:http://www.cjmb.org/pdf.php?id=514

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