Human umbilical cord mesenchymal stem cells regulate immunoglobulin a secretion and remodel the diversification of intestinal microbiota to improve colitis

Human umbilical cord mesenchymal stem cells regulate immunoglobulin a secretion and remodel the diversification of intestinal microbiota to improve colitis

BackgroundMesenchymal stem cell (MSC) therapy has emerged as a promising novel therapeutic strategy for managing inflammatory bowel disease (IBD) mainly via dampening inflammation, regulating immune disorders, and promoting mucosal tissue repair. However, in the process, the associated changes in th...

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Bibliographic Details
Main Authors: Airu Liu, Xing Wang, Xiaonan Liang, Wenxin Wang, Chenyang Li, Jiaming Qian, Xiaolan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
mesenchymal stem cells
intestinal microbiota
colitis
immunoglobulin A
16S rRNA
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.960208/full

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