Altered receptor binding, antibody evasion and retention of T cell recognition by the SARS-CoV-2 XBB.1.5 spike protein

Abstract The XBB.1.5 variant of SARS-CoV-2 has rapidly achieved global dominance and exhibits a high growth advantage over previous variants. Preliminary reports suggest that the success of XBB.1.5 stems from mutations within its spike glycoprotein, causing immune evasion and enhanced receptor bindi...

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Bibliographic Details
Main Authors: Dhiraj Mannar, James W. Saville, Chad Poloni, Xing Zhu, Alison Bezeruk, Keith Tidey, Sana Ahmed, Katharine S. Tuttle, Faezeh Vahdatihassani, Spencer Cholak, Laura Cook, Theodore S. Steiner, Sriram Subramaniam
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46104-2