Bayesian estimation in NONMEM

Abstract Bayesian estimation is a powerful but underutilized tool for answering drug development questions. In this tutorial, the principles of Bayesian model development, assessment, and prior selection will be outlined. An example pharmacokinetic (PK) model will be used to demonstrate the implemen...

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Bibliographic Details
Main Authors: Curtis K. Johnston, Timothy Waterhouse, Matthew Wiens, John Mondick, Jonathan French, William R. Gillespie
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.13088