Decoding the glycoproteome: a new frontier for biomarker discovery in cancer

Decoding the glycoproteome: a new frontier for biomarker discovery in cancer

Abstract Cancer early detection and treatment response prediction continue to pose significant challenges. Cancer liquid biopsies focusing on detecting circulating tumor cells (CTCs) and DNA (ctDNA) have shown enormous potential due to their non-invasive nature and the implications in precision canc...

Full description

Bibliographic Details
Main Authors:	Kai He, Maryam Baniasad, Hyunwoo Kwon, Tomislav Caval, Gege Xu, Carlito Lebrilla, Daniel W. Hommes, Carolyn Bertozzi
Format:	Article
Language:	English
Published:	BMC 2024-03-01
Series:	Journal of Hematology & Oncology
Subjects:	Glycoproteomics Biomarker Cancer Screening
Online Access:	https://doi.org/10.1186/s13045-024-01532-x

Similar Items

An Integrated Mass Spectrometry-Based Glycomics-Driven Glycoproteomics Analytical Platform to Functionally Characterize Glycosylation Inhibitors
by: Michael Russelle S. Alvarez, et al.
Published: (2022-06-01)

Glycomic, Glycoproteomic, and Proteomic Profiling of Philippine Lung Cancer and Peritumoral Tissues: Case Series Study of Patients Stages I–III
by: Michael Russelle Alvarez, et al.
Published: (2023-03-01)

Serum Glycoproteomic Alterations in Patients with Diabetic Retinopathy
by: Ashok Sharma, et al.
Published: (2020-09-01)

Integrated Proteomic and N-Glycoproteomic Profiling of Placental Tissues of Patients with Preeclampsia
by: Wang H, et al.
Published: (2023-01-01)

Quantitative N-glycoproteome analysis of bovine milk and yogurt
by: Jing Xiao, et al.
Published: (2022-01-01)

Lectin affinity-based glycoproteome analysis of the developing xylem in poplar
by: Hao Cheng, et al.
Published: (2022-01-01)

Glycoproteomic Analysis of Urinary Extracellular Vesicles for Biomarkers of Hepatocellular Carcinoma
by: Dejun Li, et al.
Published: (2023-01-01)

Editorial: New methods, techniques and applications in clinical glycoproteomics
by: Yong Zhang, et al.
Published: (2023-03-01)

Plasma glycoproteomic biomarkers identify metastatic melanoma patients with reduced clinical benefit from immune checkpoint inhibitor therapy
by: Chad Pickering, et al.
Published: (2023-06-01)

The Secreted Plant N-Glycoproteome and Associated Secretory Pathways
by: Eliel eRuiz-May, et al.
Published: (2012-06-01)

Expanding the Chondroitin Sulfate Glycoproteome — But How Far?
by: Fredrik Noborn, et al.
Published: (2021-08-01)

Mass Spectrometry Strategies for <i>O</i>-Glycoproteomics
by: Amanda Helms, et al.
Published: (2024-02-01)

Integrating transcriptomics, glycomics and glycoproteomics to characterize hepatitis B virus-associated hepatocellular carcinoma
by: Zhuo Li, et al.
Published: (2024-04-01)

Differential Glycosite Profiling—A Versatile Method to Compare Membrane Glycoproteomes
by: Malwina Michalak, et al.
Published: (2021-06-01)

The Need for Community Standards to Enable Accurate Comparison of Glycoproteomics Algorithm Performance
by: William E. Hackett, et al.
Published: (2021-08-01)

Integrated proteomic, phosphoproteomic, and N-glycoproteomic analyses of the longissimus thoracis of yaks
by: Xinping Chang, et al.
Published: (2022-01-01)

Fucosyltransferase 4 shapes oncogenic glycoproteome to drive metastasis of lung adenocarcinoma
by: Hsuan-Hsuan Lu, et al.
Published: (2020-07-01)

Glycoscience aids in biomarker discovery
by: Serenus Hua1,2 & Hyun Joo An1,2,*
Published: (2012-06-01)

Glycoproteomics in Cerebrospinal Fluid Reveals Brain-Specific Glycosylation Changes
by: Melissa Baerenfaenger, et al.
Published: (2023-01-01)

Glycoproteomics identifies HOMER3 as a potentially targetable biomarker triggered by hypoxia and glucose deprivation in bladder cancer
by: Andreia Peixoto, et al.
Published: (2021-06-01)

An Integrated Proteomic and Glycoproteomic Investigation Reveals Alterations in the <i>N</i>-Glycoproteomic Network Induced by 2-Deoxy-D-Glucose in Colorectal Cancer Cells
by: Cheng Ma, et al.
Published: (2022-07-01)

Comparative Profiling of Triple-Negative Breast Carcinomas Tissue Glycoproteome by Sequential Purification of Glycoproteins and Stable Isotope Labeling
by: Xiang Chen, et al.
Published: (2016-01-01)

An integrated proteomic and glycoproteomic approach uncovers differences in glycosylation occupancy from benign and malignant epithelial ovarian tumors
by: Qing Kay Li, et al.
Published: (2017-05-01)

Stool Glycoproteomics Signatures of Pre-Cancerous Lesions and Colorectal Cancer
by: Janine Soares, et al.
Published: (2024-03-01)

Defining the altered glycoproteomic space of the early secretory pathway by class I mannosidase pharmacological inhibition
by: Cristian V. A. Munteanu, et al.
Published: (2023-01-01)

Quantitative glycoproteomics reveals cellular substrate selectivity of the ER protein quality control sensors UGGT1 and UGGT2
by: Benjamin M Adams, et al.
Published: (2020-12-01)

Development of a glycoproteomic strategy to detect more aggressive prostate cancer using lectin-immunoassays for serum fucosylated PSA
by: Ce Wang, et al.
Published: (2019-04-01)

Global profiling of the proteome, phosphoproteome, and N-glycoproteome of protoscoleces and adult worms of Echinococcus granulosus
by: Zhengrong Wang, et al.
Published: (2023-11-01)

An N-glycoproteomic site-mapping analysis reveals glycoprotein alterations in esophageal squamous cell carcinoma
by: Yingzhen Gao, et al.
Published: (2022-06-01)

Precision N‐glycoproteomics reveals elevated LacdiNAc as a novel signature of intrahepatic cholangiocarcinoma
by: Jun Li, et al.
Published: (2022-06-01)

Quantitative glycoproteomics analysis identifies novel FUT8 targets and signaling networks critical for breast cancer cell invasiveness
by: Cheng-Fen Tu, et al.
Published: (2022-03-01)

Investigation of cell wall proteins of C. sinensis leaves by combining cell wall proteomics and N-glycoproteomics
by: Yanli Liu, et al.
Published: (2021-08-01)

Nascent Glycoproteome Reveals That N-Linked Glycosylation Inhibitor-1 Suppresses Expression of Glycosylated Lysosome-Associated Membrane Protein-2
by: Xinyi Cao, et al.
Published: (2022-04-01)

Targeted O-glycoproteomics for the development of diagnostic markers for advanced colorectal cancer
by: Daisuke Takakura, et al.
Published: (2023-02-01)

Comparative glycoproteomics study on the surface of SKOV3 versus IOSE80 cell lines
by: Ying Zhou, et al.
Published: (2022-11-01)

What Can N-glycomics and N-glycoproteomics of Cerebrospinal Fluid Tell Us about Alzheimer Disease?
by: Stefan Gaunitz, et al.
Published: (2021-06-01)

Integrated Proteomic and Glycoproteomic Characterization of Human High-Grade Serous Ovarian Carcinoma
by: Yingwei Hu, et al.
Published: (2020-10-01)

Discovery of a haptoglobin glycopeptides biomarker panel for early diagnosis of hepatocellular carcinoma
by: Mahdokht Kohansal-Nodehi, et al.
Published: (2023-10-01)

Overcoming Challenges and Opening New Opportunities in Glycoproteomics
by: Bruce A. Macher, et al.
Published: (2013-03-01)

Semi-Automated Glycoproteomic Data Analysis of LC-MS Data Using GlycopeptideGraphMS in Process Development of Monoclonal Antibody Biologics
by: Kuin Tian Pang, et al.
Published: (2021-05-01)