Structural insights into redox-active cysteine residues of the Src family kinases
The Src Family Kinases (SFKs) are pivotal regulators of cellular signal transduction and highly sought-after targets in drug discovery. Their actions within cells are controlled by alterations in protein phosphorylation that switch the SFKs from autoinhibited to active states. The SFKs are also well...
Main Author: | David E. Heppner |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-05-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231721000823 |
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