Evaluation of Exercise-Induced Hypertension Post Endovascular Stenting of Coarctation of Aorta
Background: Coarctation of the aorta (COA) is a defect that accounts for 5-8% of all congenital heart diseases. Balloon angioplasty as a treatment for COA is increasingly performed, with endovascular stents having been proposed as a means of improving the efficacy and safety of the procedure. The ai...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2010-08-01
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| Series: | Journal of Tehran University Heart Center |
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| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/16125.pdf&manuscript_id=16125 |
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| author | Akbar Shah Mohammadi Mohmood Meraji Paridokht Nakhostin Davary Mehdi Ghaderian Mohammad Yoosef Aarabi Moghadam Hojat Mortazaeian |
| author_facet | Akbar Shah Mohammadi Mohmood Meraji Paridokht Nakhostin Davary Mehdi Ghaderian Mohammad Yoosef Aarabi Moghadam Hojat Mortazaeian |
| author_sort | Akbar Shah Mohammadi |
| collection | DOAJ |
| description | Background: Coarctation of the aorta (COA) is a defect that accounts for 5-8% of all congenital heart diseases. Balloon angioplasty as a treatment for COA is increasingly performed, with endovascular stents having been proposed as a means of improving the efficacy and safety of the procedure. The aim of this study was to evaluate the systolic blood pressure gradient at rest and during maximal exercise at follow-up in patients post endovascular stenting of COA.Methods: Thirteen patients (4 native and 9 re-coarctation cases of COA after surgery or balloon angioplasty) with a mean age of 11.1 ± 4.7 years underwent endovascular stenting between November 2007 and December 2009 via standard techniques for native COA as an alternative to surgical repair. Doppler echocardiography was performed pre and post stenting. Resting and exercise assessment of blood pressure was performed at follow-up.Results: Post stent implantation, no angiographic major complications were evident. Systolic blood pressure gradient decreased from 42 ± 8.8 mm Hg before stent placement to 7 ± 10 mm Hg at follow-up (p value < 0.001). Peak Doppler pressure gradient decreased from 30 ± 14 mm Hg to 14 ± 10 mm Hg at follow-up (p value < 0.007). One case of exerciseinduced hypertension was seen in patients.Conclusion: Endovascular stenting for native COA in older children and post-surgical COA repair in patients with residual COA and re-coarctation is a reasonable alternative to surgical correction. During early follow-up, stenting effectively alleviates the aortic arch obstruction with normalization of the systemic blood pressure both at rest and during maximal exercise. |
| first_indexed | 2024-12-21T08:02:27Z |
| format | Article |
| id | doaj.art-ae57c3583d9741609f44aae9d230b464 |
| institution | Directory Open Access Journal |
| issn | 1735-8620 |
| language | English |
| last_indexed | 2024-12-21T08:02:27Z |
| publishDate | 2010-08-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Journal of Tehran University Heart Center |
| spelling | doaj.art-ae57c3583d9741609f44aae9d230b4642022-12-21T19:10:52ZengTehran University of Medical SciencesJournal of Tehran University Heart Center1735-86202010-08-0153137140Evaluation of Exercise-Induced Hypertension Post Endovascular Stenting of Coarctation of AortaAkbar Shah MohammadiMohmood MerajiParidokht Nakhostin DavaryMehdi GhaderianMohammad Yoosef Aarabi MoghadamHojat MortazaeianBackground: Coarctation of the aorta (COA) is a defect that accounts for 5-8% of all congenital heart diseases. Balloon angioplasty as a treatment for COA is increasingly performed, with endovascular stents having been proposed as a means of improving the efficacy and safety of the procedure. The aim of this study was to evaluate the systolic blood pressure gradient at rest and during maximal exercise at follow-up in patients post endovascular stenting of COA.Methods: Thirteen patients (4 native and 9 re-coarctation cases of COA after surgery or balloon angioplasty) with a mean age of 11.1 ± 4.7 years underwent endovascular stenting between November 2007 and December 2009 via standard techniques for native COA as an alternative to surgical repair. Doppler echocardiography was performed pre and post stenting. Resting and exercise assessment of blood pressure was performed at follow-up.Results: Post stent implantation, no angiographic major complications were evident. Systolic blood pressure gradient decreased from 42 ± 8.8 mm Hg before stent placement to 7 ± 10 mm Hg at follow-up (p value < 0.001). Peak Doppler pressure gradient decreased from 30 ± 14 mm Hg to 14 ± 10 mm Hg at follow-up (p value < 0.007). One case of exerciseinduced hypertension was seen in patients.Conclusion: Endovascular stenting for native COA in older children and post-surgical COA repair in patients with residual COA and re-coarctation is a reasonable alternative to surgical correction. During early follow-up, stenting effectively alleviates the aortic arch obstruction with normalization of the systemic blood pressure both at rest and during maximal exercise.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/16125.pdf&manuscript_id=16125Heart Defects- CongenitalAortic CoarctationStentsHypertension |
| spellingShingle | Akbar Shah Mohammadi Mohmood Meraji Paridokht Nakhostin Davary Mehdi Ghaderian Mohammad Yoosef Aarabi Moghadam Hojat Mortazaeian Evaluation of Exercise-Induced Hypertension Post Endovascular Stenting of Coarctation of Aorta Journal of Tehran University Heart Center Heart Defects- Congenital Aortic Coarctation Stents Hypertension |
| title | Evaluation of Exercise-Induced Hypertension Post Endovascular Stenting of Coarctation of Aorta |
| title_full | Evaluation of Exercise-Induced Hypertension Post Endovascular Stenting of Coarctation of Aorta |
| title_fullStr | Evaluation of Exercise-Induced Hypertension Post Endovascular Stenting of Coarctation of Aorta |
| title_full_unstemmed | Evaluation of Exercise-Induced Hypertension Post Endovascular Stenting of Coarctation of Aorta |
| title_short | Evaluation of Exercise-Induced Hypertension Post Endovascular Stenting of Coarctation of Aorta |
| title_sort | evaluation of exercise induced hypertension post endovascular stenting of coarctation of aorta |
| topic | Heart Defects- Congenital Aortic Coarctation Stents Hypertension |
| url | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/16125.pdf&manuscript_id=16125 |
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