Latin-American Registry of Cardiovascular Disease and COVID-19: Final Results

Background: Socioeconomic factors contribute to a more severe impact of COVID-19 in Latin American and Caribbean (LA&C) countries than in developed countries. Patients with a severe or critical illness can develop respiratory and cardiovascular complications. Objective: To describe a LA&C po...

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Main Authors: Juan Esteban Gomez-Mesa, Stephania Galindo, Manuela Escalante-Forero, Yorlany Rodas, Andrea Valencia, Eduardo Perna, Alexander Romero, Iván Mendoza, Fernando Wyss, José Luis Barisani, Mario Speranza, Walter Alarco, Noel Alberto Flórez
Format: Article
Language:English
Published: Ubiquity Press 2023-11-01
Series:Global Heart
Subjects:
Online Access:https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1272
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author Juan Esteban Gomez-Mesa
Stephania Galindo
Manuela Escalante-Forero
Yorlany Rodas
Andrea Valencia
Eduardo Perna
Alexander Romero
Iván Mendoza
Fernando Wyss
José Luis Barisani
Mario Speranza
Walter Alarco
Noel Alberto Flórez
author_facet Juan Esteban Gomez-Mesa
Stephania Galindo
Manuela Escalante-Forero
Yorlany Rodas
Andrea Valencia
Eduardo Perna
Alexander Romero
Iván Mendoza
Fernando Wyss
José Luis Barisani
Mario Speranza
Walter Alarco
Noel Alberto Flórez
author_sort Juan Esteban Gomez-Mesa
collection DOAJ
description Background: Socioeconomic factors contribute to a more severe impact of COVID-19 in Latin American and Caribbean (LA&C) countries than in developed countries. Patients with a severe or critical illness can develop respiratory and cardiovascular complications. Objective: To describe a LA&C population with COVID-19 to provide information related to this disease, in-hospital cardiovascular complications, and in-hospital mortality. Methods: The CARDIO COVID-19–20 Registry is an observational, multicenter, prospective, and hospital-based registry of patients with confirmed COVID-19 infection that required in-hospital treatment in LA&C. Enrollment of patients started on May 01, 2020, and ended on June 30, 2021. Results: The CARDIO COVID-19–20 Registry included 3260 patients from 44 institutions of 14 LA&C countries. 63.2% patients were male and median age was 61.0 years old. Most common comorbidities were overweight/obesity (49.7%), hypertension (49.0%), and diabetes mellitus (26.7%). Most frequent cardiovascular complications during hospitalization or reported at discharge were cardiac arrhythmia (9.1%), decompensated heart failure (8.5%), and pulmonary embolism (3.9%). The number of patients admitted to the Intensive Care Unit (ICU) was 1745 (53.5%), and median length of their stay at the ICU was 10.0 days. Support required in ICU included invasive mechanical ventilation (34.2%), vasopressors (27.6%), inotropics (10.3%), and vasodilators (3.7%). Rehospitalization after 30-day post discharge was 7.3%. In-hospital mortality and 30-day post discharge were 25.5% and 2.6%, respectively. Conclusions: According to our findings, more than half of the LA&C population with COVID-19 assessed required management in ICU, with higher requirement of invasive mechanical ventilation and vasoactive support, resulting in a high in-hospital mortality and a considerable high 30-day post discharge rehospitalization and mortality.
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spelling doaj.art-ae5ba2cb1a6940b09565ba88608dff122023-12-22T06:33:32ZengUbiquity PressGlobal Heart2211-81792023-11-01181606010.5334/gh.12721253Latin-American Registry of Cardiovascular Disease and COVID-19: Final ResultsJuan Esteban Gomez-Mesa0https://orcid.org/0000-0002-6635-6224Stephania Galindo1https://orcid.org/0000-0002-6347-0996Manuela Escalante-Forero2https://orcid.org/0000-0002-2822-0887Yorlany Rodas3https://orcid.org/0000-0002-7344-6156Andrea Valencia4https://orcid.org/0000-0001-6855-207XEduardo Perna5https://orcid.org/0000-0002-9977-7623Alexander Romero6https://orcid.org/0000-0002-0785-0804Iván Mendoza7https://orcid.org/0000-0002-9098-8424Fernando Wyss8https://orcid.org/0000-0003-1700-4692José Luis Barisani9https://orcid.org/0000-0002-2206-8466Mario Speranza10https://orcid.org/0000-0002-6947-0735Walter Alarco11https://orcid.org/0000-0001-5881-4080Noel Alberto Flórez12https://orcid.org/0000-0001-8714-7168Fundación Valle del Lili, CaliFundación Valle del Lili, CaliFundación Valle del Lili, CaliFundación Valle del Lili, CaliFundación Valle del Lili, CaliInstituto de Cardiología J.F Cabral, CorrientesHospital Santo Tomas, Ciudad de PanamaUniversidad Central de Venezuela, CaracasServicios y Tecnología Cardiovascular de Guatemala S.A – Cardiosolutions, Ciudad de GuatemalaClínica Adventista Belgrano, Buenos AiresHospital Clínica Bíblica, San JoseInstituto Nacional Cardiovascular INCOR ESSALUD, LimaFundación Valle del Lili, CaliBackground: Socioeconomic factors contribute to a more severe impact of COVID-19 in Latin American and Caribbean (LA&C) countries than in developed countries. Patients with a severe or critical illness can develop respiratory and cardiovascular complications. Objective: To describe a LA&C population with COVID-19 to provide information related to this disease, in-hospital cardiovascular complications, and in-hospital mortality. Methods: The CARDIO COVID-19–20 Registry is an observational, multicenter, prospective, and hospital-based registry of patients with confirmed COVID-19 infection that required in-hospital treatment in LA&C. Enrollment of patients started on May 01, 2020, and ended on June 30, 2021. Results: The CARDIO COVID-19–20 Registry included 3260 patients from 44 institutions of 14 LA&C countries. 63.2% patients were male and median age was 61.0 years old. Most common comorbidities were overweight/obesity (49.7%), hypertension (49.0%), and diabetes mellitus (26.7%). Most frequent cardiovascular complications during hospitalization or reported at discharge were cardiac arrhythmia (9.1%), decompensated heart failure (8.5%), and pulmonary embolism (3.9%). The number of patients admitted to the Intensive Care Unit (ICU) was 1745 (53.5%), and median length of their stay at the ICU was 10.0 days. Support required in ICU included invasive mechanical ventilation (34.2%), vasopressors (27.6%), inotropics (10.3%), and vasodilators (3.7%). Rehospitalization after 30-day post discharge was 7.3%. In-hospital mortality and 30-day post discharge were 25.5% and 2.6%, respectively. Conclusions: According to our findings, more than half of the LA&C population with COVID-19 assessed required management in ICU, with higher requirement of invasive mechanical ventilation and vasoactive support, resulting in a high in-hospital mortality and a considerable high 30-day post discharge rehospitalization and mortality.https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1272coronaviruscovid-19latin americacaribbeansars-cov-2heart failure
spellingShingle Juan Esteban Gomez-Mesa
Stephania Galindo
Manuela Escalante-Forero
Yorlany Rodas
Andrea Valencia
Eduardo Perna
Alexander Romero
Iván Mendoza
Fernando Wyss
José Luis Barisani
Mario Speranza
Walter Alarco
Noel Alberto Flórez
Latin-American Registry of Cardiovascular Disease and COVID-19: Final Results
Global Heart
coronavirus
covid-19
latin america
caribbean
sars-cov-2
heart failure
title Latin-American Registry of Cardiovascular Disease and COVID-19: Final Results
title_full Latin-American Registry of Cardiovascular Disease and COVID-19: Final Results
title_fullStr Latin-American Registry of Cardiovascular Disease and COVID-19: Final Results
title_full_unstemmed Latin-American Registry of Cardiovascular Disease and COVID-19: Final Results
title_short Latin-American Registry of Cardiovascular Disease and COVID-19: Final Results
title_sort latin american registry of cardiovascular disease and covid 19 final results
topic coronavirus
covid-19
latin america
caribbean
sars-cov-2
heart failure
url https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1272
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