Identification of a hyperinflammatory sepsis phenotype using protein biomarker and clinical data in the ProCESS randomized trial
Abstract Sepsis is a heterogeneous syndrome and phenotypes have been proposed using clinical data. Less is known about the contribution of protein biomarkers to clinical sepsis phenotypes and their importance for treatment effects in randomized trials of resuscitation. The objective is to use both c...
Main Authors: | Kimberley M. DeMerle, Jason N. Kennedy, Chung-Chou H. Chang, Kevin Delucchi, David T. Huang, Max S. Kravitz, Nathan I. Shapiro, Donald M. Yealy, Derek C. Angus, Carolyn S. Calfee, Christopher W. Seymour |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-03-01
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Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-024-55667-5 |
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