Porcine/Chicken or Human Nephropathy as the Result of Joint Mycotoxins Interaction

A survey was made of the literature concerning the occurrence and incidence of mycotoxic nephropathy in pigs and chicks in different countries. Various etiological factors contributing to the development of the disease were considered. The main nephrotoxic fungi as well as the specific conditions fo...

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Main Authors: Stefan A. Denev, Stoycho D. Stoev
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/5/9/1503
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author Stefan A. Denev
Stoycho D. Stoev
author_facet Stefan A. Denev
Stoycho D. Stoev
author_sort Stefan A. Denev
collection DOAJ
description A survey was made of the literature concerning the occurrence and incidence of mycotoxic nephropathy in pigs and chicks in different countries. Various etiological factors contributing to the development of the disease were considered. The main nephrotoxic fungi as well as the specific conditions for their growth and toxins production were briefly described. A survey was made about the most frequent nephrotoxic fungal contaminants in various feedstuffs from plant origin. In addition, their natural quantities and importance for development of mycotoxic porcine/chick nephropathy (MPN/MCN) are also explored. In addition, a survey was made of the feedstuffs representing the most favorable environment for nephrotoxic fungal growth as well as the most favorable storehouse conditions for this fungal growth were shortly described. The significance of some underestimated fungal species, which can provoke kidney damage, was studied. The importance of joint mycotoxin interaction and newly identified fungal metabolites in the complex etiology of mycotoxic nephropathy ranged in some countries is deeply investigated. The toxicity of the low contamination levels of some combinations of mycotoxins often administered by pigs and chicks in the practice was carefully studied.
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spelling doaj.art-ae5cdd67b3294a2fb4880443378ecd232022-12-22T04:24:15ZengMDPI AGToxins2072-66512013-09-01591503153010.3390/toxins5091503Porcine/Chicken or Human Nephropathy as the Result of Joint Mycotoxins InteractionStefan A. DenevStoycho D. StoevA survey was made of the literature concerning the occurrence and incidence of mycotoxic nephropathy in pigs and chicks in different countries. Various etiological factors contributing to the development of the disease were considered. The main nephrotoxic fungi as well as the specific conditions for their growth and toxins production were briefly described. A survey was made about the most frequent nephrotoxic fungal contaminants in various feedstuffs from plant origin. In addition, their natural quantities and importance for development of mycotoxic porcine/chick nephropathy (MPN/MCN) are also explored. In addition, a survey was made of the feedstuffs representing the most favorable environment for nephrotoxic fungal growth as well as the most favorable storehouse conditions for this fungal growth were shortly described. The significance of some underestimated fungal species, which can provoke kidney damage, was studied. The importance of joint mycotoxin interaction and newly identified fungal metabolites in the complex etiology of mycotoxic nephropathy ranged in some countries is deeply investigated. The toxicity of the low contamination levels of some combinations of mycotoxins often administered by pigs and chicks in the practice was carefully studied.http://www.mdpi.com/2072-6651/5/9/1503mycotoxic porcine nephropathymycotoxic chick nephropathyBalkan endemic nephropathyjoint mycotoxin effectmycotoxin interactionochratoxin Apenicillic acidfumonisin B1citrininunknown metabolite
spellingShingle Stefan A. Denev
Stoycho D. Stoev
Porcine/Chicken or Human Nephropathy as the Result of Joint Mycotoxins Interaction
Toxins
mycotoxic porcine nephropathy
mycotoxic chick nephropathy
Balkan endemic nephropathy
joint mycotoxin effect
mycotoxin interaction
ochratoxin A
penicillic acid
fumonisin B1
citrinin
unknown metabolite
title Porcine/Chicken or Human Nephropathy as the Result of Joint Mycotoxins Interaction
title_full Porcine/Chicken or Human Nephropathy as the Result of Joint Mycotoxins Interaction
title_fullStr Porcine/Chicken or Human Nephropathy as the Result of Joint Mycotoxins Interaction
title_full_unstemmed Porcine/Chicken or Human Nephropathy as the Result of Joint Mycotoxins Interaction
title_short Porcine/Chicken or Human Nephropathy as the Result of Joint Mycotoxins Interaction
title_sort porcine chicken or human nephropathy as the result of joint mycotoxins interaction
topic mycotoxic porcine nephropathy
mycotoxic chick nephropathy
Balkan endemic nephropathy
joint mycotoxin effect
mycotoxin interaction
ochratoxin A
penicillic acid
fumonisin B1
citrinin
unknown metabolite
url http://www.mdpi.com/2072-6651/5/9/1503
work_keys_str_mv AT stefanadenev porcinechickenorhumannephropathyastheresultofjointmycotoxinsinteraction
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