Safety of femtosecond laser-assisted cataract surgery versus conventional phacoemulsification for cataract: A meta-analysis and systematic review
Purpose: To compare the complications of femtosecond laser-assisted cataract surgery (FLACS) with those of conventional phacoemulsification surgery (CPS) for age-related cataracts. Methods: PubMed, Cochrane Library, and EMBASE were systematically searched for studies comparing FLACS and CPS. Outcome...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-05-01
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| Series: | Advances in Ophthalmology Practice and Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S266737622200004X |
| _version_ | 1811247844437262336 |
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| author | Jingjie Xu Xinyi Chen Hanle Wang Ke Yao |
| author_facet | Jingjie Xu Xinyi Chen Hanle Wang Ke Yao |
| author_sort | Jingjie Xu |
| collection | DOAJ |
| description | Purpose: To compare the complications of femtosecond laser-assisted cataract surgery (FLACS) with those of conventional phacoemulsification surgery (CPS) for age-related cataracts. Methods: PubMed, Cochrane Library, and EMBASE were systematically searched for studies comparing FLACS and CPS. Outcomes were operative complications, including the intraoperative capsule tear, postoperative corneal edema, macular edema, uncontrolled IOP, etc. The effect measures were weighted with odds ratios with 95% CIs. Results: Nineteen RCTs and 18 cohort studies, including 24,806 eyes (11,375 of the FLACS group and 13,431 of the CPS group), were identified. There were no significant differences between the two groups in anterior capsule tear, corneal edema, macular edema, uncontrolled IOP, vitreous loss, posterior vitreous detachment, etc. Posterior capsule tear rate showed a significantly lower in RCT subgroups (P = 0.04) and without differences in total (P = 0.63). Significant differences were observed in the incidence of descemet membrane tear/trauma (P = 0.02) and IFIS/iris trauma (P = 0.04. Additionally, The FLACS specific complications showed a significantly higher rate of miosis (P < 0.0001), corneal epithelial defect (P = 0.001), corneal haze (P = 0.002), and subconjunctival hemorrhage (P = 0.01). Conclusions: FLACS maintains the same safety compared with CPS in terms of all intraoperative and postoperative complications. Although FLACS did show a statistically significant difference for several FLACS specific complications, it would not influence the visual outcome and heal itself. |
| first_indexed | 2024-04-12T15:16:38Z |
| format | Article |
| id | doaj.art-ae6027558df7492b8710a6d3cd5586dd |
| institution | Directory Open Access Journal |
| issn | 2667-3762 |
| language | English |
| last_indexed | 2024-04-12T15:16:38Z |
| publishDate | 2022-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Advances in Ophthalmology Practice and Research |
| spelling | doaj.art-ae6027558df7492b8710a6d3cd5586dd2022-12-22T03:27:37ZengElsevierAdvances in Ophthalmology Practice and Research2667-37622022-05-0121100027Safety of femtosecond laser-assisted cataract surgery versus conventional phacoemulsification for cataract: A meta-analysis and systematic reviewJingjie Xu0Xinyi Chen1Hanle Wang2Ke Yao3Eye Center of the Second Affiliated Hospital, Medical College of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, ChinaEye Center of the Second Affiliated Hospital, Medical College of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, ChinaEye Center of the Second Affiliated Hospital, Medical College of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, ChinaCorresponding author. Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 310020, Hangzhou, China.; Eye Center of the Second Affiliated Hospital, Medical College of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, ChinaPurpose: To compare the complications of femtosecond laser-assisted cataract surgery (FLACS) with those of conventional phacoemulsification surgery (CPS) for age-related cataracts. Methods: PubMed, Cochrane Library, and EMBASE were systematically searched for studies comparing FLACS and CPS. Outcomes were operative complications, including the intraoperative capsule tear, postoperative corneal edema, macular edema, uncontrolled IOP, etc. The effect measures were weighted with odds ratios with 95% CIs. Results: Nineteen RCTs and 18 cohort studies, including 24,806 eyes (11,375 of the FLACS group and 13,431 of the CPS group), were identified. There were no significant differences between the two groups in anterior capsule tear, corneal edema, macular edema, uncontrolled IOP, vitreous loss, posterior vitreous detachment, etc. Posterior capsule tear rate showed a significantly lower in RCT subgroups (P = 0.04) and without differences in total (P = 0.63). Significant differences were observed in the incidence of descemet membrane tear/trauma (P = 0.02) and IFIS/iris trauma (P = 0.04. Additionally, The FLACS specific complications showed a significantly higher rate of miosis (P < 0.0001), corneal epithelial defect (P = 0.001), corneal haze (P = 0.002), and subconjunctival hemorrhage (P = 0.01). Conclusions: FLACS maintains the same safety compared with CPS in terms of all intraoperative and postoperative complications. Although FLACS did show a statistically significant difference for several FLACS specific complications, it would not influence the visual outcome and heal itself.http://www.sciencedirect.com/science/article/pii/S266737622200004XFemtosecond laser assisted cataract surgeryConventional phacoemulsification surgerySafetyComplicationCapsular tear rate |
| spellingShingle | Jingjie Xu Xinyi Chen Hanle Wang Ke Yao Safety of femtosecond laser-assisted cataract surgery versus conventional phacoemulsification for cataract: A meta-analysis and systematic review Advances in Ophthalmology Practice and Research Femtosecond laser assisted cataract surgery Conventional phacoemulsification surgery Safety Complication Capsular tear rate |
| title | Safety of femtosecond laser-assisted cataract surgery versus conventional phacoemulsification for cataract: A meta-analysis and systematic review |
| title_full | Safety of femtosecond laser-assisted cataract surgery versus conventional phacoemulsification for cataract: A meta-analysis and systematic review |
| title_fullStr | Safety of femtosecond laser-assisted cataract surgery versus conventional phacoemulsification for cataract: A meta-analysis and systematic review |
| title_full_unstemmed | Safety of femtosecond laser-assisted cataract surgery versus conventional phacoemulsification for cataract: A meta-analysis and systematic review |
| title_short | Safety of femtosecond laser-assisted cataract surgery versus conventional phacoemulsification for cataract: A meta-analysis and systematic review |
| title_sort | safety of femtosecond laser assisted cataract surgery versus conventional phacoemulsification for cataract a meta analysis and systematic review |
| topic | Femtosecond laser assisted cataract surgery Conventional phacoemulsification surgery Safety Complication Capsular tear rate |
| url | http://www.sciencedirect.com/science/article/pii/S266737622200004X |
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