Monkeypox Diagnosis by Cutaneous and Mucosal Findings
A monkeypox outbreak has been reported in several countries since early May 2022. Human monkeypox (MPX) diagnosis is based on a clinical suspicion supported by typical skin and mucosal lesions, confirmed with molecular testing. We present the results of all MPX confirmed patients presenting to our d...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-09-01
|
| Series: | Infectious Disease Reports |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2036-7449/14/5/77 |
| _version_ | 1827649976874827776 |
|---|---|
| author | Diogo de Sousa João Patrocínio Joana Frade Claúdia Brazão Dora Mancha Catarina Correia João Borges-Costa Paulo Filipe |
| author_facet | Diogo de Sousa João Patrocínio Joana Frade Claúdia Brazão Dora Mancha Catarina Correia João Borges-Costa Paulo Filipe |
| author_sort | Diogo de Sousa |
| collection | DOAJ |
| description | A monkeypox outbreak has been reported in several countries since early May 2022. Human monkeypox (MPX) diagnosis is based on a clinical suspicion supported by typical skin and mucosal lesions, confirmed with molecular testing. We present the results of all MPX confirmed patients presenting to our department until July 15 of 2022, describing the characteristics of the lesions at diagnosis. In total, 47 patients were included, all men and 44.7% (<i>n</i> = 21) were HIV-positive. Skin lesions were noted in all patients. The most commonly affected area was the genital region (63.8%), followed by the anorectal region (46.8%). Extra anogenital mucosal (oral or conjunctival mucosa) involvement was reported in three patients. Typical skin findings included erythematous papules, whitish, umbilicated papules, some with a necrotic center and an elevated whitish border. Most patients had lesions in multiple phases presenting simultaneously. Correct identification of MPX skin and mucosal lesions is crucial to avoid late diagnosis and prevent further spreading, ensuring less worldwide morbidity. |
| first_indexed | 2024-03-09T20:08:03Z |
| format | Article |
| id | doaj.art-ae60f70f5c664f15b59b39b9c5762b45 |
| institution | Directory Open Access Journal |
| issn | 2036-7449 |
| language | English |
| last_indexed | 2024-03-09T20:08:03Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Infectious Disease Reports |
| spelling | doaj.art-ae60f70f5c664f15b59b39b9c5762b452023-11-24T00:25:34ZengMDPI AGInfectious Disease Reports2036-74492022-09-0114575976410.3390/idr14050077Monkeypox Diagnosis by Cutaneous and Mucosal FindingsDiogo de Sousa0João Patrocínio1Joana Frade2Claúdia Brazão3Dora Mancha4Catarina Correia5João Borges-Costa6Paulo Filipe7Dermatology Department, Centro Hospitalar Universitário Lisboa Norte, 1169-050 Lisbon, PortugalDermatology Department, Centro Hospitalar Universitário Lisboa Norte, 1169-050 Lisbon, PortugalDermatology Department, Centro Hospitalar Universitário Lisboa Norte, 1169-050 Lisbon, PortugalDermatology Department, Centro Hospitalar Universitário Lisboa Norte, 1169-050 Lisbon, PortugalDermatology Department, Centro Hospitalar Universitário Lisboa Norte, 1169-050 Lisbon, PortugalDermatology Department, Centro Hospitalar Universitário Lisboa Norte, 1169-050 Lisbon, PortugalDermatology Department, Centro Hospitalar Universitário Lisboa Norte, 1169-050 Lisbon, PortugalDermatology Department, Centro Hospitalar Universitário Lisboa Norte, 1169-050 Lisbon, PortugalA monkeypox outbreak has been reported in several countries since early May 2022. Human monkeypox (MPX) diagnosis is based on a clinical suspicion supported by typical skin and mucosal lesions, confirmed with molecular testing. We present the results of all MPX confirmed patients presenting to our department until July 15 of 2022, describing the characteristics of the lesions at diagnosis. In total, 47 patients were included, all men and 44.7% (<i>n</i> = 21) were HIV-positive. Skin lesions were noted in all patients. The most commonly affected area was the genital region (63.8%), followed by the anorectal region (46.8%). Extra anogenital mucosal (oral or conjunctival mucosa) involvement was reported in three patients. Typical skin findings included erythematous papules, whitish, umbilicated papules, some with a necrotic center and an elevated whitish border. Most patients had lesions in multiple phases presenting simultaneously. Correct identification of MPX skin and mucosal lesions is crucial to avoid late diagnosis and prevent further spreading, ensuring less worldwide morbidity.https://www.mdpi.com/2036-7449/14/5/77monkeypoxskinepidemiologydisease outbreak |
| spellingShingle | Diogo de Sousa João Patrocínio Joana Frade Claúdia Brazão Dora Mancha Catarina Correia João Borges-Costa Paulo Filipe Monkeypox Diagnosis by Cutaneous and Mucosal Findings Infectious Disease Reports monkeypox skin epidemiology disease outbreak |
| title | Monkeypox Diagnosis by Cutaneous and Mucosal Findings |
| title_full | Monkeypox Diagnosis by Cutaneous and Mucosal Findings |
| title_fullStr | Monkeypox Diagnosis by Cutaneous and Mucosal Findings |
| title_full_unstemmed | Monkeypox Diagnosis by Cutaneous and Mucosal Findings |
| title_short | Monkeypox Diagnosis by Cutaneous and Mucosal Findings |
| title_sort | monkeypox diagnosis by cutaneous and mucosal findings |
| topic | monkeypox skin epidemiology disease outbreak |
| url | https://www.mdpi.com/2036-7449/14/5/77 |
| work_keys_str_mv | AT diogodesousa monkeypoxdiagnosisbycutaneousandmucosalfindings AT joaopatrocinio monkeypoxdiagnosisbycutaneousandmucosalfindings AT joanafrade monkeypoxdiagnosisbycutaneousandmucosalfindings AT claudiabrazao monkeypoxdiagnosisbycutaneousandmucosalfindings AT doramancha monkeypoxdiagnosisbycutaneousandmucosalfindings AT catarinacorreia monkeypoxdiagnosisbycutaneousandmucosalfindings AT joaoborgescosta monkeypoxdiagnosisbycutaneousandmucosalfindings AT paulofilipe monkeypoxdiagnosisbycutaneousandmucosalfindings |