Duration of protection of CoronaVac plus heterologous BNT162b2 booster in the Omicron period in Brazil
Primary CoronaVac vaccination followed by a BNT162b2 booster dose confers protection against some SARS-CoV-2 variants but its effectiveness against Omicron is unknown. Here, the authors show that this combination confers a high level of protection against severe outcomes for up to 120 days, with evi...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-31839-7 |
| _version_ | 1818190122376495104 |
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| author | Thiago Cerqueira-Silva Vinicius de Araujo Oliveira Enny S. Paixão Juracy Bertoldo Júnior Gerson O. Penna Guilherme L. Werneck Neil Pearce Maurício L. Barreto Viviane S. Boaventura Manoel Barral-Netto |
| author_facet | Thiago Cerqueira-Silva Vinicius de Araujo Oliveira Enny S. Paixão Juracy Bertoldo Júnior Gerson O. Penna Guilherme L. Werneck Neil Pearce Maurício L. Barreto Viviane S. Boaventura Manoel Barral-Netto |
| author_sort | Thiago Cerqueira-Silva |
| collection | DOAJ |
| description | Primary CoronaVac vaccination followed by a BNT162b2 booster dose confers protection against some SARS-CoV-2 variants but its effectiveness against Omicron is unknown. Here, the authors show that this combination confers a high level of protection against severe outcomes for up to 120 days, with evidence of waning for those aged 80 or older. |
| first_indexed | 2024-12-11T23:53:42Z |
| format | Article |
| id | doaj.art-ae64e24901e447b89414616d84f2020e |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-11T23:53:42Z |
| publishDate | 2022-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-ae64e24901e447b89414616d84f2020e2022-12-22T00:45:24ZengNature PortfolioNature Communications2041-17232022-07-011311610.1038/s41467-022-31839-7Duration of protection of CoronaVac plus heterologous BNT162b2 booster in the Omicron period in BrazilThiago Cerqueira-Silva0Vinicius de Araujo Oliveira1Enny S. Paixão2Juracy Bertoldo Júnior3Gerson O. Penna4Guilherme L. Werneck5Neil Pearce6Maurício L. Barreto7Viviane S. Boaventura8Manoel Barral-Netto9LIB and LEITV Laboratories, Instituto Gonçalo Moniz, FiocruzUniversidade Federal da BahiaLondon School of Hygiene and Tropical MedicineUniversidade Federal da BahiaNúcleo de Medicina Tropical, Universidade de Brasília. Escola Fiocruz de GovernoUniversidade do Estado do Rio de JaneiroLondon School of Hygiene and Tropical MedicineUniversidade Federal da BahiaLIB and LEITV Laboratories, Instituto Gonçalo Moniz, FiocruzLIB and LEITV Laboratories, Instituto Gonçalo Moniz, FiocruzPrimary CoronaVac vaccination followed by a BNT162b2 booster dose confers protection against some SARS-CoV-2 variants but its effectiveness against Omicron is unknown. Here, the authors show that this combination confers a high level of protection against severe outcomes for up to 120 days, with evidence of waning for those aged 80 or older.https://doi.org/10.1038/s41467-022-31839-7 |
| spellingShingle | Thiago Cerqueira-Silva Vinicius de Araujo Oliveira Enny S. Paixão Juracy Bertoldo Júnior Gerson O. Penna Guilherme L. Werneck Neil Pearce Maurício L. Barreto Viviane S. Boaventura Manoel Barral-Netto Duration of protection of CoronaVac plus heterologous BNT162b2 booster in the Omicron period in Brazil Nature Communications |
| title | Duration of protection of CoronaVac plus heterologous BNT162b2 booster in the Omicron period in Brazil |
| title_full | Duration of protection of CoronaVac plus heterologous BNT162b2 booster in the Omicron period in Brazil |
| title_fullStr | Duration of protection of CoronaVac plus heterologous BNT162b2 booster in the Omicron period in Brazil |
| title_full_unstemmed | Duration of protection of CoronaVac plus heterologous BNT162b2 booster in the Omicron period in Brazil |
| title_short | Duration of protection of CoronaVac plus heterologous BNT162b2 booster in the Omicron period in Brazil |
| title_sort | duration of protection of coronavac plus heterologous bnt162b2 booster in the omicron period in brazil |
| url | https://doi.org/10.1038/s41467-022-31839-7 |
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