T cells loaded with magnetic nanoparticles are retained in peripheral lymph nodes by the application of a magnetic field

T cells loaded with magnetic nanoparticles are retained in peripheral lymph nodes by the application of a magnetic field

Abstract Background T lymphocytes are highly dynamic elements of the immune system with a tightly regulated migration. T cell-based transfer therapies are promising therapeutic approaches which in vivo efficacy is often limited by the small proportion of administered cells that reaches the region of...

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Bibliographic Details
Main Authors: Laura Sanz-Ortega, José M. Rojas, Ana Marcos, Yadileiny Portilla, Jens V. Stein, Domingo F. Barber
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Nanobiotechnology
Subjects:
Cell-based therapy
T cell
Magnetic nanoparticle
Magnetic retention
Lymph node
Online Access:http://link.springer.com/article/10.1186/s12951-019-0440-z

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http://link.springer.com/article/10.1186/s12951-019-0440-z

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