The human intestinal IgA response; burning questions.
Understanding the cellular and molecular mechanisms that generate the human intestinal IgA response is fundamentally important if effective mucosal vaccination is to be successful and broadly applied. There have been several major advances in this field recently that have allowed us to feel optimis...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2012-05-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00108/full |
| _version_ | 1818340453367414784 |
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| author | Jo eSpencer Louise D Fraser |
| author_facet | Jo eSpencer Louise D Fraser |
| author_sort | Jo eSpencer |
| collection | DOAJ |
| description | Understanding the cellular and molecular mechanisms that generate the human intestinal IgA response is fundamentally important if effective mucosal vaccination is to be successful and broadly applied. There have been several major advances in this field recently that have allowed us to feel optimistic that this will be achieved. However, there are still many unanswered questions. These questions have been used as a scaffold for this review that considers findings at the current leading edge alongside the many uncertainties in this field. |
| first_indexed | 2024-12-13T15:43:08Z |
| format | Article |
| id | doaj.art-ae6bae05a01a4382a125bc29ccefae46 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-12-13T15:43:08Z |
| publishDate | 2012-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-ae6bae05a01a4382a125bc29ccefae462022-12-21T23:39:46ZengFrontiers Media S.A.Frontiers in Immunology1664-32242012-05-01310.3389/fimmu.2012.0010824230The human intestinal IgA response; burning questions.Jo eSpencer0Louise D Fraser1King's College LondonKing's College LondonUnderstanding the cellular and molecular mechanisms that generate the human intestinal IgA response is fundamentally important if effective mucosal vaccination is to be successful and broadly applied. There have been several major advances in this field recently that have allowed us to feel optimistic that this will be achieved. However, there are still many unanswered questions. These questions have been used as a scaffold for this review that considers findings at the current leading edge alongside the many uncertainties in this field.http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00108/fullhumanIgAGut-associated lymphoid tissue |
| spellingShingle | Jo eSpencer Louise D Fraser The human intestinal IgA response; burning questions. Frontiers in Immunology human IgA Gut-associated lymphoid tissue |
| title | The human intestinal IgA response; burning questions. |
| title_full | The human intestinal IgA response; burning questions. |
| title_fullStr | The human intestinal IgA response; burning questions. |
| title_full_unstemmed | The human intestinal IgA response; burning questions. |
| title_short | The human intestinal IgA response; burning questions. |
| title_sort | human intestinal iga response burning questions |
| topic | human IgA Gut-associated lymphoid tissue |
| url | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00108/full |
| work_keys_str_mv | AT joespencer thehumanintestinaligaresponseburningquestions AT louisedfraser thehumanintestinaligaresponseburningquestions AT joespencer humanintestinaligaresponseburningquestions AT louisedfraser humanintestinaligaresponseburningquestions |