Association of ABO Blood Group Antigen and Neurological Tumors
Background Various risk factors for tumors such as smoking, alcohol consumption, diet, and radiation, etc., were already identified. ABO blood group antigens are also present on epithelia, endothelia, and neurons. Recent evidence suggested the role of ABO antigens in the pathogenesis of certain mali...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2022-06-01
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| Series: | Journal of Neuroanaesthesiology and Critical Care |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1749656 |
| _version_ | 1818000821276639232 |
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| author | Gopal K. Patidar Yashaswi Dhiman Anjali Hazarika |
| author_facet | Gopal K. Patidar Yashaswi Dhiman Anjali Hazarika |
| author_sort | Gopal K. Patidar |
| collection | DOAJ |
| description | Background Various risk factors for tumors such as smoking, alcohol consumption, diet, and radiation, etc., were already identified. ABO blood group antigens are also present on epithelia, endothelia, and neurons. Recent evidence suggested the role of ABO antigens in the pathogenesis of certain malignancies.
Materials and Methods A retrospective observational study was conducted in a tertiary care neurosurgical center in North India from January 2016 to December 2018. The hospital information system was used to obtain patient information while the blood center information system was used to collect blood group information. Brain tumors were majorly divided into cavernoma, glioma, meningioma, neuroma, pituitary adenoma, schwannoma, and others.
Results We found a total of 1,970 patients with brain tumors admitted during our study period. Most patients had glioma (33.55%), followed by pituitary adenoma (20.05%) and neuroma (2.23%). B blood group individuals had more prevalence of cavernoma, glioma, meningioma, pituitary adenoma, schwannoma, and others followed by O, A, and AB. Only association of O blood group with neuroma tumor was found statistically significant.
Conclusions Our patient population had blood group distribution similar to our general population and no significant association was observed by blood group antigens and brain tumors. Although neuroma was significantly associated with blood group O but the prevalence of neuroma in our patient population is very low hence large sample study is required to draw a firm conclusion regarding this association. |
| first_indexed | 2024-04-14T03:26:33Z |
| format | Article |
| id | doaj.art-ae72cc4c691c416aa6c25c04c4d9d0f2 |
| institution | Directory Open Access Journal |
| issn | 2348-0548 2348-926X |
| language | English |
| last_indexed | 2024-04-14T03:26:33Z |
| publishDate | 2022-06-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Journal of Neuroanaesthesiology and Critical Care |
| spelling | doaj.art-ae72cc4c691c416aa6c25c04c4d9d0f22022-12-22T02:15:09ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Neuroanaesthesiology and Critical Care2348-05482348-926X2022-06-01090209309810.1055/s-0042-1749656Association of ABO Blood Group Antigen and Neurological TumorsGopal K. Patidar0Yashaswi Dhiman1Anjali Hazarika2Department of Transfusion Medicine, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Immunohematology and Blood Transfusion, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, IndiaDepartment of Transfusion Medicine, All India Institute of Medical Sciences, New Delhi, IndiaBackground Various risk factors for tumors such as smoking, alcohol consumption, diet, and radiation, etc., were already identified. ABO blood group antigens are also present on epithelia, endothelia, and neurons. Recent evidence suggested the role of ABO antigens in the pathogenesis of certain malignancies. Materials and Methods A retrospective observational study was conducted in a tertiary care neurosurgical center in North India from January 2016 to December 2018. The hospital information system was used to obtain patient information while the blood center information system was used to collect blood group information. Brain tumors were majorly divided into cavernoma, glioma, meningioma, neuroma, pituitary adenoma, schwannoma, and others. Results We found a total of 1,970 patients with brain tumors admitted during our study period. Most patients had glioma (33.55%), followed by pituitary adenoma (20.05%) and neuroma (2.23%). B blood group individuals had more prevalence of cavernoma, glioma, meningioma, pituitary adenoma, schwannoma, and others followed by O, A, and AB. Only association of O blood group with neuroma tumor was found statistically significant. Conclusions Our patient population had blood group distribution similar to our general population and no significant association was observed by blood group antigens and brain tumors. Although neuroma was significantly associated with blood group O but the prevalence of neuroma in our patient population is very low hence large sample study is required to draw a firm conclusion regarding this association.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1749656blood groupsneurological tumorsassociationneuroma |
| spellingShingle | Gopal K. Patidar Yashaswi Dhiman Anjali Hazarika Association of ABO Blood Group Antigen and Neurological Tumors Journal of Neuroanaesthesiology and Critical Care blood groups neurological tumors association neuroma |
| title | Association of ABO Blood Group Antigen and Neurological Tumors |
| title_full | Association of ABO Blood Group Antigen and Neurological Tumors |
| title_fullStr | Association of ABO Blood Group Antigen and Neurological Tumors |
| title_full_unstemmed | Association of ABO Blood Group Antigen and Neurological Tumors |
| title_short | Association of ABO Blood Group Antigen and Neurological Tumors |
| title_sort | association of abo blood group antigen and neurological tumors |
| topic | blood groups neurological tumors association neuroma |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1749656 |
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