How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis
Any living cell parasitizing a host organism is immersed into a molecular environment of unfathomable complex- ity. For the advancement of its life cycle in such “hostile” a territory, the cell has to carefully sense its environment, “see” the ongoing physiological processes taking place, and guide...
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Format: | Article |
Language: | English |
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Paderborn University: Media Systems and Media Organisation Research Group
2011-10-01
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Series: | tripleC: Communication, Capitalism & Critique |
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Online Access: | https://www.triple-c.at/index.php/tripleC/article/view/292 |
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author | Jorge Navarro Pedro C. Marijuán |
author_facet | Jorge Navarro Pedro C. Marijuán |
author_sort | Jorge Navarro |
collection | DOAJ |
description | Any living cell parasitizing a host organism is immersed into a molecular environment of unfathomable complex- ity. For the advancement of its life cycle in such “hostile” a territory, the cell has to carefully sense its environment, “see” the ongoing physiological processes taking place, and guide subsequently its own network of self-construction processes, pathological responses included. We will discuss how this informational matching occurs in the bacillus Mycobacterium tuberculosis, and how transcriptional programs within the global transcriptional regulatory network are deployed in response to specific signals from the environment and from within the cell itself. In the era of the bioinformatic revolution and of sys- tems biology, it is perhaps surprising that the functional interconnection between the transcription network and the signaling system is far from clarified yet. In the extent to which the living cell can be considered as one of the central paradigms of the nascent information science, this discussion also becomes one about the essential cluster of concepts which should poten- tially apply to the analysis of other information-based entities. |
first_indexed | 2024-03-12T06:09:57Z |
format | Article |
id | doaj.art-ae792a121e594916a5beaa387b2fcaf0 |
institution | Directory Open Access Journal |
issn | 1726-670X 1726-670X |
language | English |
last_indexed | 2024-03-12T06:09:57Z |
publishDate | 2011-10-01 |
publisher | Paderborn University: Media Systems and Media Organisation Research Group |
record_format | Article |
series | tripleC: Communication, Capitalism & Critique |
spelling | doaj.art-ae792a121e594916a5beaa387b2fcaf02023-09-03T03:07:09ZengPaderborn University: Media Systems and Media Organisation Research GrouptripleC: Communication, Capitalism & Critique1726-670X1726-670X2011-10-019239640310.31269/triplec.v9i2.292292How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium TuberculosisJorge NavarroPedro C. MarijuánAny living cell parasitizing a host organism is immersed into a molecular environment of unfathomable complex- ity. For the advancement of its life cycle in such “hostile” a territory, the cell has to carefully sense its environment, “see” the ongoing physiological processes taking place, and guide subsequently its own network of self-construction processes, pathological responses included. We will discuss how this informational matching occurs in the bacillus Mycobacterium tuberculosis, and how transcriptional programs within the global transcriptional regulatory network are deployed in response to specific signals from the environment and from within the cell itself. In the era of the bioinformatic revolution and of sys- tems biology, it is perhaps surprising that the functional interconnection between the transcription network and the signaling system is far from clarified yet. In the extent to which the living cell can be considered as one of the central paradigms of the nascent information science, this discussion also becomes one about the essential cluster of concepts which should poten- tially apply to the analysis of other information-based entities.https://www.triple-c.at/index.php/tripleC/article/view/292Mycobacterium tuberculosistranscriptional regulatory networksignaling systeminformation and meaningknowledge recombination |
spellingShingle | Jorge Navarro Pedro C. Marijuán How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis tripleC: Communication, Capitalism & Critique Mycobacterium tuberculosis transcriptional regulatory network signaling system information and meaning knowledge recombination |
title | How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis |
title_full | How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis |
title_fullStr | How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis |
title_full_unstemmed | How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis |
title_short | How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis |
title_sort | how a bacillus sees the world information needs and signaling resources of mycobacterium tuberculosis |
topic | Mycobacterium tuberculosis transcriptional regulatory network signaling system information and meaning knowledge recombination |
url | https://www.triple-c.at/index.php/tripleC/article/view/292 |
work_keys_str_mv | AT jorgenavarro howabacillusseestheworldinformationneedsandsignalingresourcesofmycobacteriumtuberculosis AT pedrocmarijuan howabacillusseestheworldinformationneedsandsignalingresourcesofmycobacteriumtuberculosis |