How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis

Any living cell parasitizing a host organism is immersed into a molecular environment of unfathomable complex- ity. For the advancement of its life cycle in such “hostile” a territory, the cell has to carefully sense its environment, “see” the ongoing physiological processes taking place, and guide...

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Main Authors: Jorge Navarro, Pedro C. Marijuán
Format: Article
Language:English
Published: Paderborn University: Media Systems and Media Organisation Research Group 2011-10-01
Series:tripleC: Communication, Capitalism & Critique
Subjects:
Online Access:https://www.triple-c.at/index.php/tripleC/article/view/292
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author Jorge Navarro
Pedro C. Marijuán
author_facet Jorge Navarro
Pedro C. Marijuán
author_sort Jorge Navarro
collection DOAJ
description Any living cell parasitizing a host organism is immersed into a molecular environment of unfathomable complex- ity. For the advancement of its life cycle in such “hostile” a territory, the cell has to carefully sense its environment, “see” the ongoing physiological processes taking place, and guide subsequently its own network of self-construction processes, pathological responses included. We will discuss how this informational matching occurs in the bacillus Mycobacterium tuberculosis, and how transcriptional programs within the global transcriptional regulatory network are deployed in response to specific signals from the environment and from within the cell itself. In the era of the bioinformatic revolution and of sys- tems biology, it is perhaps surprising that the functional interconnection between the transcription network and the signaling system is far from clarified yet. In the extent to which the living cell can be considered as one of the central paradigms of the nascent information science, this discussion also becomes one about the essential cluster of concepts which should poten- tially apply to the analysis of other information-based entities.
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spelling doaj.art-ae792a121e594916a5beaa387b2fcaf02023-09-03T03:07:09ZengPaderborn University: Media Systems and Media Organisation Research GrouptripleC: Communication, Capitalism & Critique1726-670X1726-670X2011-10-019239640310.31269/triplec.v9i2.292292How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium TuberculosisJorge NavarroPedro C. MarijuánAny living cell parasitizing a host organism is immersed into a molecular environment of unfathomable complex- ity. For the advancement of its life cycle in such “hostile” a territory, the cell has to carefully sense its environment, “see” the ongoing physiological processes taking place, and guide subsequently its own network of self-construction processes, pathological responses included. We will discuss how this informational matching occurs in the bacillus Mycobacterium tuberculosis, and how transcriptional programs within the global transcriptional regulatory network are deployed in response to specific signals from the environment and from within the cell itself. In the era of the bioinformatic revolution and of sys- tems biology, it is perhaps surprising that the functional interconnection between the transcription network and the signaling system is far from clarified yet. In the extent to which the living cell can be considered as one of the central paradigms of the nascent information science, this discussion also becomes one about the essential cluster of concepts which should poten- tially apply to the analysis of other information-based entities.https://www.triple-c.at/index.php/tripleC/article/view/292Mycobacterium tuberculosistranscriptional regulatory networksignaling systeminformation and meaningknowledge recombination
spellingShingle Jorge Navarro
Pedro C. Marijuán
How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis
tripleC: Communication, Capitalism & Critique
Mycobacterium tuberculosis
transcriptional regulatory network
signaling system
information and meaning
knowledge recombination
title How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis
title_full How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis
title_fullStr How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis
title_full_unstemmed How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis
title_short How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis
title_sort how a bacillus sees the world information needs and signaling resources of mycobacterium tuberculosis
topic Mycobacterium tuberculosis
transcriptional regulatory network
signaling system
information and meaning
knowledge recombination
url https://www.triple-c.at/index.php/tripleC/article/view/292
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