Preclinical and Clinical Evidence of Therapeutic Agents for Paclitaxel-Induced Peripheral Neuropathy

Preclinical and Clinical Evidence of Therapeutic Agents for Paclitaxel-Induced Peripheral Neuropathy

Paclitaxel is an essential drug in the chemotherapy of ovarian, non-small cell lung, breast, gastric, endometrial, and pancreatic cancers. However, it frequently causes peripheral neuropathy as a dose-limiting factor. Animal models of paclitaxel-induced peripheral neuropathy (PIPN) have been establi...

Full description

Bibliographic Details
Main Authors:	Takehiro Kawashiri, Mizuki Inoue, Kohei Mori, Daisuke Kobayashi, Keisuke Mine, Soichiro Ushio, Hibiki Kudamatsu, Mayako Uchida, Nobuaki Egashira, Takao Shimazoe
Format:	Article
Language:	English
Published:	MDPI AG 2021-08-01
Series:	International Journal of Molecular Sciences
Subjects:	paclitaxel peripheral neuropathy preclinical data clinical evidence adverse effects
Online Access:	https://www.mdpi.com/1422-0067/22/16/8733

Similar Items

Inhibitory Effect of α1 Receptor Antagonists on Paclitaxel-Induced Peripheral Neuropathy in a Rodent Model and Clinical Database
by: Kohei Mori, et al.
Published: (2022-11-01)

Therapeutic Agents for Oxaliplatin-Induced Peripheral Neuropathy; Experimental and Clinical Evidence
by: Takehiro Kawashiri, et al.
Published: (2021-01-01)

Polaprezinc reduces paclitaxel-induced peripheral neuropathy in rats without affecting anti-tumor activity
by: Kuniaki Tsutsumi, et al.
Published: (2016-06-01)

Omeprazole Suppresses Oxaliplatin-Induced Peripheral Neuropathy in a Rodent Model and Clinical Database
by: Keisuke Mine, et al.
Published: (2022-08-01)

Pathomechanisms of Paclitaxel-Induced Peripheral Neuropathy
by: Ines Klein, et al.
Published: (2021-09-01)

The effect of Sargassum glaucescens from the Persian gulf on neuropathy pain induced by paclitaxel in mice
by: Afsaneh Yegdaneh, et al.
Published: (2020-01-01)

Ameliorating effects of cystine and theanine in a cancer cachexia mouse model
by: Hibiki Kudamatsu, et al.
Published: (2023-07-01)

Behavioral and pharmacological characteristics of bortezomib-induced peripheral neuropathy in rats
by: Shota Yamamoto, et al.
Published: (2015-09-01)

Goshajinkigan reduces bortezomib-induced mechanical allodynia in rats: Possible involvement of kappa opioid receptor
by: Hitomi Higuchi, et al.
Published: (2015-11-01)

Comparison of Peripheral Neuropathy Induced by Standard and Nanoparticle Albumin–Bound Paclitaxel in Rats
by: Yuji Yamashita, et al.
Published: (2011-01-01)

Nmnat mitigates sensory dysfunction in a Drosophila model of paclitaxel-induced peripheral neuropathy
by: Jennifer M. Brazill, et al.
Published: (2018-06-01)

Paclitaxel Inhibits KCNQ Channels in Primary Sensory Neurons to Initiate the Development of Painful Peripheral Neuropathy
by: Zizhen Wu, et al.
Published: (2022-12-01)

Longitudinal RNA Sequencing of Skin and DRG Neurons in Mice with Paclitaxel-Induced Peripheral Neuropathy
by: Anthony M. Cirrincione, et al.
Published: (2022-05-01)

Drug Repositioning for the Prevention and Treatment of Chemotherapy-Induced Peripheral Neuropathy: A Mechanism- and Screening-Based Strategy
by: Shota Yamamoto, et al.
Published: (2021-01-01)

The Antinociceptive Responses of MTDZ to Paclitaxel−Induced Peripheral Neuropathy and Acute Nociception in Mice: Behavioral, Pharmacological, and Biochemical Approaches
by: Ketlyn P. da Motta, et al.
Published: (2023-08-01)

A Fenofibrate Diet Prevents Paclitaxel-Induced Peripheral Neuropathy in Mice
by: Martial Caillaud, et al.
Published: (2020-12-01)

Estrogen decline is a risk factor for paclitaxel-induced peripheral neuropathy: Clinical evidence supported by a preclinical study
by: Tomoyoshi Miyamoto, et al.
Published: (2021-05-01)

Protective effects of oxytocin and progesterone on paclitaxel-induced neuropathy in rats
by: Mehmet Ekici, et al.
Published: (2021-01-01)

Management of paclitaxel-induced neurotoxicity
by: Manisha Bhutani, et al.
Published: (2011-12-01)

Genetic variations that influence paclitaxel pharmacokinetics and intracellular effects that may contribute to chemotherapy-induced neuropathy: A narrative review
by: Ken B. Johnson, et al.
Published: (2023-05-01)

Risk factors of paclitaxel-induced peripheral neuropathy in patients with breast cancer: a prospective cohort study
by: Sun Lixian, et al.
Published: (2024-03-01)

Randomized double-blind, placebo-controlled study of oral gabapentin for prevention of neuropathy in patients receiving paclitaxel
by: Praful Pandey, et al.
Published: (2023-02-01)

Impact of Exogenous Neurotropic Factor Administration on Occurrence and Severity of Paclitaxel-Induce Neuropathy in Breast Cancer Patients. An open label Pilot Study.
by: Mahmoud Ellithy, et al.
Published: (2018-12-01)

Blood neurofilament light chain as a biomarker for monitoring and predicting paclitaxel-induced peripheral neuropathy in patients with gynecological cancers
by: Su-Hyun Kim, et al.
Published: (2022-08-01)

Polygenic risk of paclitaxel-induced peripheral neuropathy: a genome-wide association study
by: Kosar Hooshmand, et al.
Published: (2022-12-01)

The Comparison of Neutropenia and Peripheral Neuropathy Condition as an Impact of 3-hours and 24-hour Paclitaxel Infusion of Paclitaxel-Carboplatin Chemotherapy on Ovarian Cancer Patients
by: Primandono Perbowo, et al.
Published: (2019-07-01)

Corrigendum: Blood neurofilament light chain as a biomarker for monitoring and predicting paclitaxel-induced peripheral neuropathy in patients with gynecological cancers
by: Su-Hyun Kim, et al.
Published: (2023-09-01)

Corydalis saxicola Bunting total alkaloids attenuate paclitaxel-induced peripheral neuropathy through PKCε/p38 MAPK/TRPV1 signaling pathway
by: Chu Xue, et al.
Published: (2021-07-01)

Oral Administration of Glutathione Trisulfide Increases Reactive Sulfur Levels in Dorsal Root Ganglion and Ameliorates Paclitaxel-Induced Peripheral Neuropathy in Mice
by: Mariko Ezaka, et al.
Published: (2022-10-01)

Skin Extracellular Matrix Breakdown Following Paclitaxel Therapy in Patients with Chemotherapy-Induced Peripheral Neuropathy
by: Nathan P. Staff, et al.
Published: (2023-08-01)

The PINK1 Activator Niclosamide Mitigates Mitochondrial Dysfunction and Thermal Hypersensitivity in a Paclitaxel-Induced <i>Drosophila</i> Model of Peripheral Neuropathy
by: Hye-Ji Jang, et al.
Published: (2022-04-01)

Pathophysiology of Chemotherapy-Induced Peripheral Neuropathy
by: Hana Starobova, et al.
Published: (2017-05-01)

Kamishoyosan and Shakuyakukanzoto promote recovery from paclitaxel-induced neurite retraction in PC12 cells
by: Ken Konaka, et al.
Published: (2017-07-01)

The Role of Interleukin-20 in Paclitaxel-Associated Peripheral Neuropathy in Non-Metastatic Breast Cancer Patients Receiving Chemotherapy
by: Kubilay Karaboyun, et al.
Published: (2023-11-01)

Omega-3 fatty acids are protective against paclitaxel-induced peripheral neuropathy: A randomized double-blind placebo controlled trial
by: Ghoreishi Zohreh, et al.
Published: (2012-08-01)

Paclitaxel effects on axonal localization and vesicular trafficking of NaV1.8
by: Christopher A. Baker, et al.
Published: (2023-02-01)

Fecal Microbiota Transplantation Alleviated Paclitaxel-Induced Peripheral Neuropathy by Interfering with Astrocytes and TLR4/p38MAPK Pathway in Rats
by: Shi H, et al.
Published: (2023-07-01)

Gabapentin and Duloxetine Prevent Oxaliplatin- and Paclitaxel-Induced Peripheral Neuropathy by Inhibiting Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Phosphorylation in Spinal Cords of Mice
by: Natsuki Kato, et al.
Published: (2020-12-01)

Effect of Melatonin on Paclitaxel-Associated Acute and Chronic Pain: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
by: Naeeme Talaee, et al.
Published: (2022-10-01)

Use of omeprazole, the proton pump inhibitor, as a potential therapy for the capecitabine-induced hand-foot syndrome
by: Shiori Hiromoto, et al.
Published: (2021-04-01)