Comparative Study of the Genetic Diversity of Local Steppe Cattle Breeds from Russia, Kazakhstan and Kyrgyzstan by Microsatellite Analysis of Museum and Modern Samples
The comparative molecular genetic study of museum and modern representatives of cattle breeds can help to elucidate the origin and maintenance of historical genetic components in modern populations. We generated the consensus genotypes for 11 microsatellite loci for 24 museum samples of Kalmyk, Kyrg...
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MDPI AG
2021-07-01
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| author | Alexandra S. Abdelmanova Veronika R. Kharzinova Valeria V. Volkova Arsen V. Dotsev Alexander A. Sermyagin Oksana I. Boronetskaya Roman Yu. Chinarov Evgeniya M. Lutshikhina Johann Sölkner Gottfried Brem Natalia A. Zinovieva |
| author_facet | Alexandra S. Abdelmanova Veronika R. Kharzinova Valeria V. Volkova Arsen V. Dotsev Alexander A. Sermyagin Oksana I. Boronetskaya Roman Yu. Chinarov Evgeniya M. Lutshikhina Johann Sölkner Gottfried Brem Natalia A. Zinovieva |
| author_sort | Alexandra S. Abdelmanova |
| collection | DOAJ |
| description | The comparative molecular genetic study of museum and modern representatives of cattle breeds can help to elucidate the origin and maintenance of historical genetic components in modern populations. We generated the consensus genotypes for 11 microsatellite loci for 24 museum samples of Kalmyk, Kyrgyz, and Kazakh cattle, dated from the first quarter of the 20th century, and compared them with those of modern Kalmyk, Kyrgyz, and Kazakh white-headed breeds. The level of genetic diversity of the modern Kalmyk and Kyrgyz cattle (uHe = 0.771–0.778) was similar to those observed in the museum samples (uHe = 0.772–0.776), while a visible decrease in genetic variability in the modern Kazakh white-headed breed compared to museum Kazakh cattle was detected (uHe = 0.726 and 0.767, respectively). The PCA plot, <i>F</i><sub>ST</sub>- and Jost’s D-based networks, and STRUCTURE clustering provided strong evidence of the maintenance of the historical genetic background in modern populations of Kalmyk and Kyrgyz cattle. In spite of the allele pool of Kazakh white-headed cattle having undergone great changes compared to the museum Kazakh cattle, several animals still carry the visible aspect of the historical genetic components. Our results can be used for the selection of individuals for the creation of gene banks and may significantly improve the efficiency of conservation programs aimed at preserving genetic diversity in the national genetic resources of cattle. |
| first_indexed | 2024-03-10T08:52:53Z |
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| institution | Directory Open Access Journal |
| issn | 1424-2818 |
| language | English |
| last_indexed | 2024-03-10T08:52:53Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diversity |
| spelling | doaj.art-ae7b2909c6444bf9af3f17af4baa4e352023-11-22T07:21:53ZengMDPI AGDiversity1424-28182021-07-0113835110.3390/d13080351Comparative Study of the Genetic Diversity of Local Steppe Cattle Breeds from Russia, Kazakhstan and Kyrgyzstan by Microsatellite Analysis of Museum and Modern SamplesAlexandra S. Abdelmanova0Veronika R. Kharzinova1Valeria V. Volkova2Arsen V. Dotsev3Alexander A. Sermyagin4Oksana I. Boronetskaya5Roman Yu. Chinarov6Evgeniya M. Lutshikhina7Johann Sölkner8Gottfried Brem9Natalia A. Zinovieva10L.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132 Podolsk, RussiaL.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132 Podolsk, RussiaL.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132 Podolsk, RussiaL.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132 Podolsk, RussiaL.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132 Podolsk, RussiaMuseum of Livestock Named after E.F. Liskun, Timiryazev Russian State Agrarian University—Moscow Agrarian Academy, ul. Timiryazevskaya 49, 127550 Moscow, RussiaL.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132 Podolsk, RussiaInstitute of Biotechnology, National Academy of Science of Kyrgyz Republic, Bishkek 720071, KyrgyzstanDivision of Livestock Sciences, University of Natural Resources and Life Sciences, 1180 Vienna, AustriaInstitute of Animal Breeding and Genetics, University of Veterinary Medicine (VMU), Veterinärplatz, 1210 Vienna, AustriaL.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132 Podolsk, RussiaThe comparative molecular genetic study of museum and modern representatives of cattle breeds can help to elucidate the origin and maintenance of historical genetic components in modern populations. We generated the consensus genotypes for 11 microsatellite loci for 24 museum samples of Kalmyk, Kyrgyz, and Kazakh cattle, dated from the first quarter of the 20th century, and compared them with those of modern Kalmyk, Kyrgyz, and Kazakh white-headed breeds. The level of genetic diversity of the modern Kalmyk and Kyrgyz cattle (uHe = 0.771–0.778) was similar to those observed in the museum samples (uHe = 0.772–0.776), while a visible decrease in genetic variability in the modern Kazakh white-headed breed compared to museum Kazakh cattle was detected (uHe = 0.726 and 0.767, respectively). The PCA plot, <i>F</i><sub>ST</sub>- and Jost’s D-based networks, and STRUCTURE clustering provided strong evidence of the maintenance of the historical genetic background in modern populations of Kalmyk and Kyrgyz cattle. In spite of the allele pool of Kazakh white-headed cattle having undergone great changes compared to the museum Kazakh cattle, several animals still carry the visible aspect of the historical genetic components. Our results can be used for the selection of individuals for the creation of gene banks and may significantly improve the efficiency of conservation programs aimed at preserving genetic diversity in the national genetic resources of cattle.https://www.mdpi.com/1424-2818/13/8/351cattleKalmyk cattleKyrgyz cattleKazakh cattleKazakh white-headed breedhistorical specimens |
| spellingShingle | Alexandra S. Abdelmanova Veronika R. Kharzinova Valeria V. Volkova Arsen V. Dotsev Alexander A. Sermyagin Oksana I. Boronetskaya Roman Yu. Chinarov Evgeniya M. Lutshikhina Johann Sölkner Gottfried Brem Natalia A. Zinovieva Comparative Study of the Genetic Diversity of Local Steppe Cattle Breeds from Russia, Kazakhstan and Kyrgyzstan by Microsatellite Analysis of Museum and Modern Samples Diversity cattle Kalmyk cattle Kyrgyz cattle Kazakh cattle Kazakh white-headed breed historical specimens |
| title | Comparative Study of the Genetic Diversity of Local Steppe Cattle Breeds from Russia, Kazakhstan and Kyrgyzstan by Microsatellite Analysis of Museum and Modern Samples |
| title_full | Comparative Study of the Genetic Diversity of Local Steppe Cattle Breeds from Russia, Kazakhstan and Kyrgyzstan by Microsatellite Analysis of Museum and Modern Samples |
| title_fullStr | Comparative Study of the Genetic Diversity of Local Steppe Cattle Breeds from Russia, Kazakhstan and Kyrgyzstan by Microsatellite Analysis of Museum and Modern Samples |
| title_full_unstemmed | Comparative Study of the Genetic Diversity of Local Steppe Cattle Breeds from Russia, Kazakhstan and Kyrgyzstan by Microsatellite Analysis of Museum and Modern Samples |
| title_short | Comparative Study of the Genetic Diversity of Local Steppe Cattle Breeds from Russia, Kazakhstan and Kyrgyzstan by Microsatellite Analysis of Museum and Modern Samples |
| title_sort | comparative study of the genetic diversity of local steppe cattle breeds from russia kazakhstan and kyrgyzstan by microsatellite analysis of museum and modern samples |
| topic | cattle Kalmyk cattle Kyrgyz cattle Kazakh cattle Kazakh white-headed breed historical specimens |
| url | https://www.mdpi.com/1424-2818/13/8/351 |
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