African evolutionary history inferred from whole genome sequence data of 44 indigenous African populations

African evolutionary history inferred from whole genome sequence data of 44 indigenous African populations

Abstract Background Africa is the origin of modern humans within the past 300 thousand years. To infer the complex demographic history of African populations and adaptation to diverse environments, we sequenced the genomes of 92 individuals from 44 indigenous African populations. Results Genetic str...

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Bibliographic Details
Main Authors: Shaohua Fan, Derek E. Kelly, Marcia H. Beltrame, Matthew E. B. Hansen, Swapan Mallick, Alessia Ranciaro, Jibril Hirbo, Simon Thompson, William Beggs, Thomas Nyambo, Sabah A. Omar, Dawit Wolde Meskel, Gurja Belay, Alain Froment, Nick Patterson, David Reich, Sarah A. Tishkoff
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Genome Biology
Subjects:
African populations
Genomic variation
Human evolution
Local adaptation
Demographic history
Effective population size
Online Access:http://link.springer.com/article/10.1186/s13059-019-1679-2

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