Bioelectric Interface Technologies in Cells and Organoids
Abstract The past two decades have witnessed breakthroughs in cellular‐scale bioelectronics and their widespread applications in life sciences, creating many powerful platforms for studying organisms directly and efficiently. These advanced devices can integrate seamlessly and intimately onto/into t...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley-VCH
2023-12-01
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| Series: | Advanced Materials Interfaces |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/admi.202300550 |
| _version_ | 1797378832080044032 |
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| author | Zhaoguo Xue Jianzhong Zhao |
| author_facet | Zhaoguo Xue Jianzhong Zhao |
| author_sort | Zhaoguo Xue |
| collection | DOAJ |
| description | Abstract The past two decades have witnessed breakthroughs in cellular‐scale bioelectronics and their widespread applications in life sciences, creating many powerful platforms for studying organisms directly and efficiently. These advanced devices can integrate seamlessly and intimately onto/into target cells and organoids, providing unprecedented functions and revolutionary capabilities. Bioelectronics with nanostructured designs are developed to allow for long‐term, stable monitoring of electrophysiological activities. This review summarizes nanostructured bioelectronics for cell electrophysiology recording, emphasizing the crucial roles of structural designs on functions and capabilities, e.g., intracellular access, high‐density multiplexed recording, multifunctional interfaces and the conformability to curvy biological shapes. Finally, the remaining challenges and opportunities in nanostructured bioelectronics are identified, and perspectives on the future developments toward their practical applications are provided. |
| first_indexed | 2024-03-08T20:12:19Z |
| format | Article |
| id | doaj.art-ae81a9e404ca46ba8839cf5e9128e649 |
| institution | Directory Open Access Journal |
| issn | 2196-7350 |
| language | English |
| last_indexed | 2024-03-08T20:12:19Z |
| publishDate | 2023-12-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | Advanced Materials Interfaces |
| spelling | doaj.art-ae81a9e404ca46ba8839cf5e9128e6492023-12-23T04:43:29ZengWiley-VCHAdvanced Materials Interfaces2196-73502023-12-011036n/an/a10.1002/admi.202300550Bioelectric Interface Technologies in Cells and OrganoidsZhaoguo Xue0Jianzhong Zhao1National Key Laboratory of Strength and Structural Integrity Institute of Solid Mechanics School of Aeronautic Science and Engineering Beihang University Beijing 100191 P. R. ChinaApplied Mechanics Laboratory Laboratory of Flexible Electronics Technology Department of Engineering Mechanics Tsinghua University Beijing 100084 P. R. ChinaAbstract The past two decades have witnessed breakthroughs in cellular‐scale bioelectronics and their widespread applications in life sciences, creating many powerful platforms for studying organisms directly and efficiently. These advanced devices can integrate seamlessly and intimately onto/into target cells and organoids, providing unprecedented functions and revolutionary capabilities. Bioelectronics with nanostructured designs are developed to allow for long‐term, stable monitoring of electrophysiological activities. This review summarizes nanostructured bioelectronics for cell electrophysiology recording, emphasizing the crucial roles of structural designs on functions and capabilities, e.g., intracellular access, high‐density multiplexed recording, multifunctional interfaces and the conformability to curvy biological shapes. Finally, the remaining challenges and opportunities in nanostructured bioelectronics are identified, and perspectives on the future developments toward their practical applications are provided.https://doi.org/10.1002/admi.202300550bioelectronicselectrophysiology recordingnanoprobesnanostructuresstructural designs |
| spellingShingle | Zhaoguo Xue Jianzhong Zhao Bioelectric Interface Technologies in Cells and Organoids Advanced Materials Interfaces bioelectronics electrophysiology recording nanoprobes nanostructures structural designs |
| title | Bioelectric Interface Technologies in Cells and Organoids |
| title_full | Bioelectric Interface Technologies in Cells and Organoids |
| title_fullStr | Bioelectric Interface Technologies in Cells and Organoids |
| title_full_unstemmed | Bioelectric Interface Technologies in Cells and Organoids |
| title_short | Bioelectric Interface Technologies in Cells and Organoids |
| title_sort | bioelectric interface technologies in cells and organoids |
| topic | bioelectronics electrophysiology recording nanoprobes nanostructures structural designs |
| url | https://doi.org/10.1002/admi.202300550 |
| work_keys_str_mv | AT zhaoguoxue bioelectricinterfacetechnologiesincellsandorganoids AT jianzhongzhao bioelectricinterfacetechnologiesincellsandorganoids |