Evaluation of the Consequences of Targeted or Focused Mini-Incision Parathyroidectomy in Patients With Primary Hyperparathyroidism
Surgical approaches to primary hyperparathyroidism (PHPT) have been associated with a change from invasive to non-invasive methods in the last 20 years. In this cross-sectional descriptive study, 55 patients with primary adenoma-induced HPT underwent surgery. The parathyroid gland in patients with...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2023-01-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/9702 |
| _version_ | 1797902831948136448 |
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| author | Hossein Hemmati Yousha Pourahmadi Behrang Motamed Mohammad Taghi Ashoobi Habib Eslami Kenarsari |
| author_facet | Hossein Hemmati Yousha Pourahmadi Behrang Motamed Mohammad Taghi Ashoobi Habib Eslami Kenarsari |
| author_sort | Hossein Hemmati |
| collection | DOAJ |
| description |
Surgical approaches to primary hyperparathyroidism (PHPT) have been associated with a change from invasive to non-invasive methods in the last 20 years. In this cross-sectional descriptive study, 55 patients with primary adenoma-induced HPT underwent surgery. The parathyroid gland in patients with primary hyperparathyroidism caused by parathyroid adenoma was removed by open surgery with an incision of about 2 cm in the neck in a targeted manner in a site localized by ultrasound or Sestamibi scan. The patients' personal information, including age, sex, length of hospital stay, serum calcium and parathyroid hormone (PTH) levels, success rate, and problems and unwanted adverse consequences of surgery (e.g. infection and bleeding) were recorded for each patient and collected information was analyzed in SPSS software. Most patients were women (80%) and individuals in the age range of 41-60 years (47.3%). The hospital stay length ranged from 2 to 5 days with an average of 3.25±0.9 days. Success was considered as a decrease in PTH and calcium levels during the first 24 h after the intervention, and success rates of 100, 98.2, and 69.1%, respectively, were evaluated for a reduction of at least 50% in PTH levels and less than 40 ng/ml of PTH levels. No major complications were reported in the studied patients. Wilcoxon test revealed significant decreases in patients' postoperative serum calcium and PTH levels (P=0.000). Mini-incision Parathyroidectomy with limited incision was associated with significant reductions in serum calcium and PTD without complications.
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| first_indexed | 2024-04-10T09:23:35Z |
| format | Article |
| id | doaj.art-ae8730e6df884e3398528a0032d0f8f9 |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-04-10T09:23:35Z |
| publishDate | 2023-01-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-ae8730e6df884e3398528a0032d0f8f92023-02-20T08:35:33ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942023-01-01601210.18502/acta.v60i12.11826Evaluation of the Consequences of Targeted or Focused Mini-Incision Parathyroidectomy in Patients With Primary HyperparathyroidismHossein Hemmati0Yousha Pourahmadi1Behrang Motamed2Mohammad Taghi Ashoobi3Habib Eslami Kenarsari4Department of Vascular Surgery, Guilan University of Medical Sciences, Rasht, Iran. AND Razi Clinical Research Development Unit, Guilan University of Medical Sciences, Rasht, IranRazi Clinical Research Development Unit, Guilan University of Medical Sciences, Rasht, IranDepartment of Internal Medicine, Inflammatory Lung Diseases Research Center, Razi Hospital, Guilan University of Medical Sciences, Rasht, IranDepartment of Vascular Surgery, Guilan University of Medical Sciences, Rasht, IranRazi Clinical Research Development Unit, Guilan University of Medical Sciences, Rasht, Iran Surgical approaches to primary hyperparathyroidism (PHPT) have been associated with a change from invasive to non-invasive methods in the last 20 years. In this cross-sectional descriptive study, 55 patients with primary adenoma-induced HPT underwent surgery. The parathyroid gland in patients with primary hyperparathyroidism caused by parathyroid adenoma was removed by open surgery with an incision of about 2 cm in the neck in a targeted manner in a site localized by ultrasound or Sestamibi scan. The patients' personal information, including age, sex, length of hospital stay, serum calcium and parathyroid hormone (PTH) levels, success rate, and problems and unwanted adverse consequences of surgery (e.g. infection and bleeding) were recorded for each patient and collected information was analyzed in SPSS software. Most patients were women (80%) and individuals in the age range of 41-60 years (47.3%). The hospital stay length ranged from 2 to 5 days with an average of 3.25±0.9 days. Success was considered as a decrease in PTH and calcium levels during the first 24 h after the intervention, and success rates of 100, 98.2, and 69.1%, respectively, were evaluated for a reduction of at least 50% in PTH levels and less than 40 ng/ml of PTH levels. No major complications were reported in the studied patients. Wilcoxon test revealed significant decreases in patients' postoperative serum calcium and PTH levels (P=0.000). Mini-incision Parathyroidectomy with limited incision was associated with significant reductions in serum calcium and PTD without complications. https://acta.tums.ac.ir/index.php/acta/article/view/9702ParathyroidectomyMinimally invasive surgeryHyperparathyroidismSuccessComplications |
| spellingShingle | Hossein Hemmati Yousha Pourahmadi Behrang Motamed Mohammad Taghi Ashoobi Habib Eslami Kenarsari Evaluation of the Consequences of Targeted or Focused Mini-Incision Parathyroidectomy in Patients With Primary Hyperparathyroidism Acta Medica Iranica Parathyroidectomy Minimally invasive surgery Hyperparathyroidism Success Complications |
| title | Evaluation of the Consequences of Targeted or Focused Mini-Incision Parathyroidectomy in Patients With Primary Hyperparathyroidism |
| title_full | Evaluation of the Consequences of Targeted or Focused Mini-Incision Parathyroidectomy in Patients With Primary Hyperparathyroidism |
| title_fullStr | Evaluation of the Consequences of Targeted or Focused Mini-Incision Parathyroidectomy in Patients With Primary Hyperparathyroidism |
| title_full_unstemmed | Evaluation of the Consequences of Targeted or Focused Mini-Incision Parathyroidectomy in Patients With Primary Hyperparathyroidism |
| title_short | Evaluation of the Consequences of Targeted or Focused Mini-Incision Parathyroidectomy in Patients With Primary Hyperparathyroidism |
| title_sort | evaluation of the consequences of targeted or focused mini incision parathyroidectomy in patients with primary hyperparathyroidism |
| topic | Parathyroidectomy Minimally invasive surgery Hyperparathyroidism Success Complications |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/9702 |
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