Comparison of different endophthalmitis prophylactic measures in cataract surgery - An analysis of 2.4 lakh cases
Purpose: To compare different endophthalmitis prophylaxis methods adopted in cataract surgery (manual small-incision cataract surgery and phacoemulsification) between the years 2013 and 2021 in the community eye care section of a tertiary eye care hospital in South India and report their outcomes. M...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=11;spage=4000;epage=4002;aulast=Reddy |
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| author | Jagadeesh Kumar Reddy Vandhana Sundaram Samruddhi Dani Neeraj Shah Ameya Ingawale C M Pooja |
| author_facet | Jagadeesh Kumar Reddy Vandhana Sundaram Samruddhi Dani Neeraj Shah Ameya Ingawale C M Pooja |
| author_sort | Jagadeesh Kumar Reddy |
| collection | DOAJ |
| description | Purpose: To compare different endophthalmitis prophylaxis methods adopted in cataract surgery (manual small-incision cataract surgery and phacoemulsification) between the years 2013 and 2021 in the community eye care section of a tertiary eye care hospital in South India and report their outcomes. Methods: All cataract surgeries performed from January 2013 to December 2021 (2,46,874 surgeries) at a single center were included in this retrospective study. The different endophthalmitis rates with each regimen were analyzed and evaluated. Results: 70,081 surgeries were performed from January 2013 to February 2015, where Tobramycin was added to Balanced Salt Solution (BSS) (Group A). From March 2015 to January 2017, 63,245 surgeries were performed when intracameral Moxifloxacin was given (Group B). From February 2017 to December 2021, 1,13,548 surgeries were performed were Amikacin was added to BSS (Group C). In total, 42 cases of postoperative endophthalmitis were reported during the study period (0.02%). There was no significant difference in the endophthalmitis rates between groups A and B (P = 0.4152); however, there was a significant decrease in endophthalmitis rates in group C when compared with group A (P = 0.04) and group B (P = 0.006). Conclusion: There was a significant reduction in the rates of endophthalmitis following the addition of amikacin in irrigating BSS. Nocardia was one of the predominant organisms isolated from these endophthalmitis patients. This is the first single-center study to report a comparative analysis of different endophthalmitis prophylactic measures in a community eye care set up with a high incidence of Nocardia endophthalmitis prevented with amikacin in BSS irrigating solution. |
| first_indexed | 2024-04-11T16:28:25Z |
| format | Article |
| id | doaj.art-ae87f4c749fb4179a0ffe22354d12b0f |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-04-11T16:28:25Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-ae87f4c749fb4179a0ffe22354d12b0f2022-12-22T04:14:06ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892022-01-0170114000400210.4103/ijo.IJO_1596_22Comparison of different endophthalmitis prophylactic measures in cataract surgery - An analysis of 2.4 lakh casesJagadeesh Kumar ReddyVandhana SundaramSamruddhi DaniNeeraj ShahAmeya IngawaleC M PoojaPurpose: To compare different endophthalmitis prophylaxis methods adopted in cataract surgery (manual small-incision cataract surgery and phacoemulsification) between the years 2013 and 2021 in the community eye care section of a tertiary eye care hospital in South India and report their outcomes. Methods: All cataract surgeries performed from January 2013 to December 2021 (2,46,874 surgeries) at a single center were included in this retrospective study. The different endophthalmitis rates with each regimen were analyzed and evaluated. Results: 70,081 surgeries were performed from January 2013 to February 2015, where Tobramycin was added to Balanced Salt Solution (BSS) (Group A). From March 2015 to January 2017, 63,245 surgeries were performed when intracameral Moxifloxacin was given (Group B). From February 2017 to December 2021, 1,13,548 surgeries were performed were Amikacin was added to BSS (Group C). In total, 42 cases of postoperative endophthalmitis were reported during the study period (0.02%). There was no significant difference in the endophthalmitis rates between groups A and B (P = 0.4152); however, there was a significant decrease in endophthalmitis rates in group C when compared with group A (P = 0.04) and group B (P = 0.006). Conclusion: There was a significant reduction in the rates of endophthalmitis following the addition of amikacin in irrigating BSS. Nocardia was one of the predominant organisms isolated from these endophthalmitis patients. This is the first single-center study to report a comparative analysis of different endophthalmitis prophylactic measures in a community eye care set up with a high incidence of Nocardia endophthalmitis prevented with amikacin in BSS irrigating solution.http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=11;spage=4000;epage=4002;aulast=Reddyamikacinendophthalmitismanual small-incision cataract surgerymoxifloxacin |
| spellingShingle | Jagadeesh Kumar Reddy Vandhana Sundaram Samruddhi Dani Neeraj Shah Ameya Ingawale C M Pooja Comparison of different endophthalmitis prophylactic measures in cataract surgery - An analysis of 2.4 lakh cases Indian Journal of Ophthalmology amikacin endophthalmitis manual small-incision cataract surgery moxifloxacin |
| title | Comparison of different endophthalmitis prophylactic measures in cataract surgery - An analysis of 2.4 lakh cases |
| title_full | Comparison of different endophthalmitis prophylactic measures in cataract surgery - An analysis of 2.4 lakh cases |
| title_fullStr | Comparison of different endophthalmitis prophylactic measures in cataract surgery - An analysis of 2.4 lakh cases |
| title_full_unstemmed | Comparison of different endophthalmitis prophylactic measures in cataract surgery - An analysis of 2.4 lakh cases |
| title_short | Comparison of different endophthalmitis prophylactic measures in cataract surgery - An analysis of 2.4 lakh cases |
| title_sort | comparison of different endophthalmitis prophylactic measures in cataract surgery an analysis of 2 4 lakh cases |
| topic | amikacin endophthalmitis manual small-incision cataract surgery moxifloxacin |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=11;spage=4000;epage=4002;aulast=Reddy |
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