The Effect of Obturator Nerve Blockade on Oncological Outcomes of Patients with Lateral Wall Localized Non-Muscle Invasive Bladder Cancer
Objective:To investigate the effect of obturator nerve blockade on oncological outcomes of patients with a diagnosis of lateral wall localized non-muscle invasive bladder cancer.Materials and Methods:One hundred six patients diagnosed with lateral wall localized non-invasive bladder cancer were eval...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2023-09-01
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| Series: | Journal of Urological Surgery |
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http://jurolsurgery.org/archives/archive-detail/article-preview/the-effect-of-obturator-nerve-blockade-on-oncologi/61292
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| author | Mustafa Ozan Horsanali Hüseyin Eren Eyüp Dil Alper Çağlayan Özgür Erdoğan Sermin Karaarslan Hakan Aygün |
| author_facet | Mustafa Ozan Horsanali Hüseyin Eren Eyüp Dil Alper Çağlayan Özgür Erdoğan Sermin Karaarslan Hakan Aygün |
| author_sort | Mustafa Ozan Horsanali |
| collection | DOAJ |
| description | Objective:To investigate the effect of obturator nerve blockade on oncological outcomes of patients with a diagnosis of lateral wall localized non-muscle invasive bladder cancer.Materials and Methods:One hundred six patients diagnosed with lateral wall localized non-invasive bladder cancer were evaluated between January 2015 and March 2020 in this retrospective, cross-sectional observational study. The patients were divided into two groups: patients receiving only spinal anesthesia and those receiving spinal anesthesia combined with ultrasound-guided obturator nerve blockade. Oncological outcomes of the groups were compared statistically.Results:We observed recurrent tumors in 25 patients (45.5%) in Group 1 and 11 patients (21.6%) in Group 2. Additionally, we observed tumor progression in eight patients (14.5%) in Group 1 and two patients (3.9%) in Group 2. We observed statistical significance in differences between groups regarding tumor size, recurrence rate, adequate muscle tissue sampling, ability for complete resection, and persistent obturator reflex. The efficacy rate of obturator blockade was 92.1% in Group 2. One-year recurrence-free survival (RFS) was 98.0% and 5-year RFS was 23.5% for Group 1, while for Group 2, they were 97.4% and 57.2%, respectively.Conclusion:The obturator reflex is a common and challenging reflex that may cause major complications and result in unintended consequences, such as incomplete resection or tumor recurrence with transurethral resection of bladder tumors. In this study, we demonstrated that combining spinal anesthesia with obturator nerve blockade for lateral wall localized non-muscle invasive bladder cancer may prevent tumor recurrence and reduce peroperative complications. |
| first_indexed | 2024-03-12T00:56:28Z |
| format | Article |
| id | doaj.art-ae88241a53494ec3970ee7b284273faa |
| institution | Directory Open Access Journal |
| issn | 2148-9580 |
| language | English |
| last_indexed | 2024-03-12T00:56:28Z |
| publishDate | 2023-09-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Journal of Urological Surgery |
| spelling | doaj.art-ae88241a53494ec3970ee7b284273faa2023-09-14T13:04:31ZengGalenos YayineviJournal of Urological Surgery2148-95802023-09-0110319920510.4274/jus.galenos.2023.2022.007413049054The Effect of Obturator Nerve Blockade on Oncological Outcomes of Patients with Lateral Wall Localized Non-Muscle Invasive Bladder CancerMustafa Ozan Horsanali0Hüseyin Eren1Eyüp Dil2Alper Çağlayan3Özgür Erdoğan4Sermin Karaarslan5Hakan Aygün6 İzmir Bakırçay University Faculty of Medicine, Department of Urology, İzmir, Turkiye Recep Tayyip Erdoğan University Faculty of Medicine, Department of Urology, Rize, Turkiye Recep Tayyip Erdoğan University Faculty of Medicine, Department of Urology, Rize, Turkiye İzmir Bakırçay University Çiğli Training and Research Hospital, Clinic of Urology, İzmir, Turkiye İzmir Bakırçay University Çiğli Training and Research Hospital, Clinic of Urology, İzmir, Turkiye İzmir Bakırçay University Çiğli Training and Research Hospital, Clinic of Anesthesiology and Reanimation, İzmir, Turkiye İzmir Bakırçay University Çiğli Training and Research Hospital, Clinic of Anesthesiology and Reanimation, İzmir, Turkiye Objective:To investigate the effect of obturator nerve blockade on oncological outcomes of patients with a diagnosis of lateral wall localized non-muscle invasive bladder cancer.Materials and Methods:One hundred six patients diagnosed with lateral wall localized non-invasive bladder cancer were evaluated between January 2015 and March 2020 in this retrospective, cross-sectional observational study. The patients were divided into two groups: patients receiving only spinal anesthesia and those receiving spinal anesthesia combined with ultrasound-guided obturator nerve blockade. Oncological outcomes of the groups were compared statistically.Results:We observed recurrent tumors in 25 patients (45.5%) in Group 1 and 11 patients (21.6%) in Group 2. Additionally, we observed tumor progression in eight patients (14.5%) in Group 1 and two patients (3.9%) in Group 2. We observed statistical significance in differences between groups regarding tumor size, recurrence rate, adequate muscle tissue sampling, ability for complete resection, and persistent obturator reflex. The efficacy rate of obturator blockade was 92.1% in Group 2. One-year recurrence-free survival (RFS) was 98.0% and 5-year RFS was 23.5% for Group 1, while for Group 2, they were 97.4% and 57.2%, respectively.Conclusion:The obturator reflex is a common and challenging reflex that may cause major complications and result in unintended consequences, such as incomplete resection or tumor recurrence with transurethral resection of bladder tumors. In this study, we demonstrated that combining spinal anesthesia with obturator nerve blockade for lateral wall localized non-muscle invasive bladder cancer may prevent tumor recurrence and reduce peroperative complications. http://jurolsurgery.org/archives/archive-detail/article-preview/the-effect-of-obturator-nerve-blockade-on-oncologi/61292 bladder cancernon-muscle invasive bladder cancerobturator nerve blockadeadductor contractionbladder perforationand nerve block |
| spellingShingle | Mustafa Ozan Horsanali Hüseyin Eren Eyüp Dil Alper Çağlayan Özgür Erdoğan Sermin Karaarslan Hakan Aygün The Effect of Obturator Nerve Blockade on Oncological Outcomes of Patients with Lateral Wall Localized Non-Muscle Invasive Bladder Cancer Journal of Urological Surgery bladder cancer non-muscle invasive bladder cancer obturator nerve blockade adductor contraction bladder perforation and nerve block |
| title | The Effect of Obturator Nerve Blockade on Oncological Outcomes of Patients with Lateral Wall Localized Non-Muscle Invasive Bladder Cancer |
| title_full | The Effect of Obturator Nerve Blockade on Oncological Outcomes of Patients with Lateral Wall Localized Non-Muscle Invasive Bladder Cancer |
| title_fullStr | The Effect of Obturator Nerve Blockade on Oncological Outcomes of Patients with Lateral Wall Localized Non-Muscle Invasive Bladder Cancer |
| title_full_unstemmed | The Effect of Obturator Nerve Blockade on Oncological Outcomes of Patients with Lateral Wall Localized Non-Muscle Invasive Bladder Cancer |
| title_short | The Effect of Obturator Nerve Blockade on Oncological Outcomes of Patients with Lateral Wall Localized Non-Muscle Invasive Bladder Cancer |
| title_sort | effect of obturator nerve blockade on oncological outcomes of patients with lateral wall localized non muscle invasive bladder cancer |
| topic | bladder cancer non-muscle invasive bladder cancer obturator nerve blockade adductor contraction bladder perforation and nerve block |
| url |
http://jurolsurgery.org/archives/archive-detail/article-preview/the-effect-of-obturator-nerve-blockade-on-oncologi/61292
|
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