Prevalence and Intensity of Vesicoureteral Reflux in Children with UTI based on Direct Radionuclide Cystography
Background: Urinary tract infection (UTI) is considered one of the most common types of infection in children. Vesicoureteral reflux (VUR) is one of the major risk factors of UTI leading to renal scarring. Cur-rently, two diagnostic methods are used for the evaluation of VUR, including voiding cysto...
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| Format: | Article |
| Language: | English |
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Bushehr University of Medical Sciences
2024-03-01
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| Series: | Iranian South Medical Journal |
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| Online Access: | http://ismj.bpums.ac.ir/article-1-1860-en.pdf |
| _version_ | 1827298817266941952 |
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| author | Esmaeil Gharepapagh Fariba Aryanpour Ashraf Fakhari Shahram Dabiri Oskui |
| author_facet | Esmaeil Gharepapagh Fariba Aryanpour Ashraf Fakhari Shahram Dabiri Oskui |
| author_sort | Esmaeil Gharepapagh |
| collection | DOAJ |
| description | Background: Urinary tract infection (UTI) is considered one of the most common types of infection in children. Vesicoureteral reflux (VUR) is one of the major risk factors of UTI leading to renal scarring. Cur-rently, two diagnostic methods are used for the evaluation of VUR, including voiding cystourethrography (VCUG) and radionuclide cystourethrography (DRNC). The present study examines the prevalence and intensity of VUR using direct radionuclide cystography (DRNC) in children referred to the Nuclear Medi-cine Division of Imam Reza Hospital in Tabriz, Iran.
Materials and Methods: The referred patients were studied by DRNC in filling, post filling, voiding and post voiding phases if there was confirmed VUR or not. Furthermore, VCUG, sonography and urine cul-ture had been performed for all the patients prior to our investigation. Both dynamic and static imaging were performed from the bladder, ureters and kidneys. The results were studied by a nuclear medicine physician to assess VUR and grade it.
Results: The prevalence of VUR among all 300 patients was calculated to be 29.3%. Most of the cases of VUR were unilateral (63.6%), among which involvement of the left kidney (42%) was significantly more frequent (p=0.022). The most common grade in the cases with unilateral involvement was grade B, and in those with bilateral involvement, grade C. The highest frequency of VUR was observed in the age group below 1 year (10%, n=30), followed by 1-4 years and 5-8 years, each with the frequency of 8.67% (n=26). There was no significant difference in terms of frequency of VUR based on age (p=0.198).
Conclusion: Our study showed that there is no significant association between VUR and urine culture results, but there is significant association between sonography/clinical findings and VUR. Moreover, the results demonstrated that DRNC is more sensitive than VCUG in the detection of VUR. |
| first_indexed | 2024-04-24T15:22:40Z |
| format | Article |
| id | doaj.art-ae8c74a411654369bcc38d6efc5a9917 |
| institution | Directory Open Access Journal |
| issn | 1735-4374 1735-6954 |
| language | English |
| last_indexed | 2024-04-24T15:22:40Z |
| publishDate | 2024-03-01 |
| publisher | Bushehr University of Medical Sciences |
| record_format | Article |
| series | Iranian South Medical Journal |
| spelling | doaj.art-ae8c74a411654369bcc38d6efc5a99172024-04-02T07:32:42ZengBushehr University of Medical SciencesIranian South Medical Journal1735-43741735-69542024-03-01264248259Prevalence and Intensity of Vesicoureteral Reflux in Children with UTI based on Direct Radionuclide CystographyEsmaeil Gharepapagh0Fariba Aryanpour1Ashraf Fakhari2Shahram Dabiri Oskui3 Medical Radiation Sciences Research Team, Tabriz University of Medical Sciences, Tabriz, Iran<br>Department of Nuclear Medicine, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran Medical Radiation Sciences Research Team, Tabriz University of Medical Sciences, Tabriz, Iran<br>Department of Nuclear Medicine, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran Medical Radiation Sciences Research Team, Tabriz University of Medical Sciences, Tabriz, Iran<br>Department of Nuclear Medicine, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran Medical Radiation Sciences Research Team, Tabriz University of Medical Sciences, Tabriz, Iran<br>Department of Nuclear Medicine, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran Background: Urinary tract infection (UTI) is considered one of the most common types of infection in children. Vesicoureteral reflux (VUR) is one of the major risk factors of UTI leading to renal scarring. Cur-rently, two diagnostic methods are used for the evaluation of VUR, including voiding cystourethrography (VCUG) and radionuclide cystourethrography (DRNC). The present study examines the prevalence and intensity of VUR using direct radionuclide cystography (DRNC) in children referred to the Nuclear Medi-cine Division of Imam Reza Hospital in Tabriz, Iran. Materials and Methods: The referred patients were studied by DRNC in filling, post filling, voiding and post voiding phases if there was confirmed VUR or not. Furthermore, VCUG, sonography and urine cul-ture had been performed for all the patients prior to our investigation. Both dynamic and static imaging were performed from the bladder, ureters and kidneys. The results were studied by a nuclear medicine physician to assess VUR and grade it. Results: The prevalence of VUR among all 300 patients was calculated to be 29.3%. Most of the cases of VUR were unilateral (63.6%), among which involvement of the left kidney (42%) was significantly more frequent (p=0.022). The most common grade in the cases with unilateral involvement was grade B, and in those with bilateral involvement, grade C. The highest frequency of VUR was observed in the age group below 1 year (10%, n=30), followed by 1-4 years and 5-8 years, each with the frequency of 8.67% (n=26). There was no significant difference in terms of frequency of VUR based on age (p=0.198). Conclusion: Our study showed that there is no significant association between VUR and urine culture results, but there is significant association between sonography/clinical findings and VUR. Moreover, the results demonstrated that DRNC is more sensitive than VCUG in the detection of VUR.http://ismj.bpums.ac.ir/article-1-1860-en.pdfurinary tract infectionvesicoureteral refluxvoiding cystourethrographyradionuclide cystourethrography |
| spellingShingle | Esmaeil Gharepapagh Fariba Aryanpour Ashraf Fakhari Shahram Dabiri Oskui Prevalence and Intensity of Vesicoureteral Reflux in Children with UTI based on Direct Radionuclide Cystography Iranian South Medical Journal urinary tract infection vesicoureteral reflux voiding cystourethrography radionuclide cystourethrography |
| title | Prevalence and Intensity of Vesicoureteral Reflux in Children with UTI based on Direct Radionuclide Cystography |
| title_full | Prevalence and Intensity of Vesicoureteral Reflux in Children with UTI based on Direct Radionuclide Cystography |
| title_fullStr | Prevalence and Intensity of Vesicoureteral Reflux in Children with UTI based on Direct Radionuclide Cystography |
| title_full_unstemmed | Prevalence and Intensity of Vesicoureteral Reflux in Children with UTI based on Direct Radionuclide Cystography |
| title_short | Prevalence and Intensity of Vesicoureteral Reflux in Children with UTI based on Direct Radionuclide Cystography |
| title_sort | prevalence and intensity of vesicoureteral reflux in children with uti based on direct radionuclide cystography |
| topic | urinary tract infection vesicoureteral reflux voiding cystourethrography radionuclide cystourethrography |
| url | http://ismj.bpums.ac.ir/article-1-1860-en.pdf |
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