Profiling of Extracellular Small RNAs Highlights a Strong Bias towards Non-Vesicular Secretion

Profiling of Extracellular Small RNAs Highlights a Strong Bias towards Non-Vesicular Secretion

The extracellular environment consists of a plethora of molecules, including extracellular miRNA that can be secreted in association with extracellular vesicles (EVs) or soluble protein complexes (non-EVs). Yet, interest in therapeutic short RNA carriers lies mainly in EVs, the vehicles conveying th...

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Bibliographic Details
Main Authors: Helena Sork, Mariana Conceicao, Giulia Corso, Joel Nordin, Yi Xin Fiona Lee, Kaarel Krjutskov, Jakub Orzechowski Westholm, Pieter Vader, Marie Pauwels, Roosmarijn E. Vandenbroucke, Matthew JA Wood, Samir EL Andaloussi, Imre Mäger
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
extracellular vesicles
small RNA
SEC
extracellular RNA
miRNA
Online Access:https://www.mdpi.com/2073-4409/10/6/1543

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