Loss of endothelial cell-specific autophagy-related protein 7 exacerbates doxorubicin-induced cardiotoxicity

Loss of endothelial cell-specific autophagy-related protein 7 exacerbates doxorubicin-induced cardiotoxicity

Doxorubicin (DOX) is an effective, broad-spectrum antineoplastic agent with serious cardiotoxic side effects, which may lead to the development of heart failure. Current strategies to diagnose, prevent, and treat DOX-induced cardiotoxicity (DIC) are inadequate. Recent evidence has linked the dysregu...

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Bibliographic Details
Main Authors: Albert Z. Luu, Vincent Z. Luu, Biswajit Chowdhury, Andrew Kosmopoulos, Yi Pan, Mohammed Al-Omran, Adrian Quan, Hwee Teoh, David A. Hess, Subodh Verma
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Autophagy
Cardiomyopathy
Doxorubicin
Endothelium
Heart failure
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821000200

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