Different MAPT haplotypes influence expression of total MAPT in postmortem brain tissue
Abstract The MAPT gene, encoding the microtubule-associated protein tau on chromosome 17q21.31, is result of an inversion polymorphism, leading to two allelic variants (H1 and H2). Homozygosity for the more common haplotype H1 is associated with an increased risk for several tauopathies, but also fo...
| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
BMC
2023-03-01
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| シリーズ: | Acta Neuropathologica Communications |
| 主題: | |
| オンライン･アクセス: | https://doi.org/10.1186/s40478-023-01534-9 |