Clinical validation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections in ICU practice: a promising diagnostic tool

Clinical validation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections in ICU practice: a promising diagnostic tool

Abstract Background Droplet digital PCR (ddPCR) has emerged as a promising tool of pathogen detection in bloodstream infections (BSIs) in critical care medicine. However, different ddPCR platforms have variable sensitivity and specificity for diverse microorganisms at various infection sites. There...

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Bibliographic Details
Main Authors: Jing Wu, Bin Tang, Yuzhen Qiu, Ruoming Tan, Jialin Liu, Jiang Xia, Jing Zhang, Jingjing Huang, Jieming Qu, Jingyong Sun, Xiaoli Wang, Hongping Qu
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Critical Care
Subjects:
Clinical validation
Droplet digital PCR
Bloodstream infections (BSIs)
Critically ill patients
Discordant results
Online Access:https://doi.org/10.1186/s13054-022-04116-8

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