Testosterone therapy with Testopel® and the Esoterix Laboratory assay: A CASE study
We present a patient receiving Testopel® implants whose serum testosterone levels, as measured by a CDC certified assay, were accurately predicted by a multi-compartmental model. This is the first time a model has predicted measured serum testosterone levels within 4% of values calculated. To our kn...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-09-01
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| Series: | Urology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442021001546 |
| _version_ | 1818590072509825024 |
|---|---|
| author | David Seitman Joseph Fallon Barry Kimmel |
| author_facet | David Seitman Joseph Fallon Barry Kimmel |
| author_sort | David Seitman |
| collection | DOAJ |
| description | We present a patient receiving Testopel® implants whose serum testosterone levels, as measured by a CDC certified assay, were accurately predicted by a multi-compartmental model. This is the first time a model has predicted measured serum testosterone levels within 4% of values calculated. To our knowledge, it was also the first time a pharmacokinetic model allowed patient targeted serum levels (peak/trough/average) to be reached within three months. |
| first_indexed | 2024-12-16T09:50:44Z |
| format | Article |
| id | doaj.art-aea088a14a324898809080ef9242c39d |
| institution | Directory Open Access Journal |
| issn | 2214-4420 |
| language | English |
| last_indexed | 2024-12-16T09:50:44Z |
| publishDate | 2021-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj.art-aea088a14a324898809080ef9242c39d2022-12-21T22:36:04ZengElsevierUrology Case Reports2214-44202021-09-0138101714Testosterone therapy with Testopel® and the Esoterix Laboratory assay: A CASE studyDavid Seitman0Joseph Fallon1Barry Kimmel23 Cara Ct., Northfield, NJ, 08225, USA; Corresponding author.Department of Medicine at Rowan University in Sewell, NJ, USAChief of Division of Urology at Cape Regional Medical Center in Cape May, Courthouse, NJ, USAWe present a patient receiving Testopel® implants whose serum testosterone levels, as measured by a CDC certified assay, were accurately predicted by a multi-compartmental model. This is the first time a model has predicted measured serum testosterone levels within 4% of values calculated. To our knowledge, it was also the first time a pharmacokinetic model allowed patient targeted serum levels (peak/trough/average) to be reached within three months.http://www.sciencedirect.com/science/article/pii/S2214442021001546Case reportPharmacokineticsTestosterone pelletsTestosterone replacement therapy |
| spellingShingle | David Seitman Joseph Fallon Barry Kimmel Testosterone therapy with Testopel® and the Esoterix Laboratory assay: A CASE study Urology Case Reports Case report Pharmacokinetics Testosterone pellets Testosterone replacement therapy |
| title | Testosterone therapy with Testopel® and the Esoterix Laboratory assay: A CASE study |
| title_full | Testosterone therapy with Testopel® and the Esoterix Laboratory assay: A CASE study |
| title_fullStr | Testosterone therapy with Testopel® and the Esoterix Laboratory assay: A CASE study |
| title_full_unstemmed | Testosterone therapy with Testopel® and the Esoterix Laboratory assay: A CASE study |
| title_short | Testosterone therapy with Testopel® and the Esoterix Laboratory assay: A CASE study |
| title_sort | testosterone therapy with testopel r and the esoterix laboratory assay a case study |
| topic | Case report Pharmacokinetics Testosterone pellets Testosterone replacement therapy |
| url | http://www.sciencedirect.com/science/article/pii/S2214442021001546 |
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