Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion
Abstract The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (Tex) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion...
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| Format: | Article |
| Language: | English |
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Wiley
2023-09-01
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| Series: | Physiological Reports |
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| Online Access: | https://doi.org/10.14814/phy2.15801 |
| _version_ | 1827389749840576512 |
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| author | Natalya Potolitsyna Olga Parshukova Nadezhda Vakhnina Nadezhda Alisultanova Lubov Kalikova Anastasia Tretyakova Alexey Chernykh Vera Shadrina Arina Duryagina Evgeny Bojko |
| author_facet | Natalya Potolitsyna Olga Parshukova Nadezhda Vakhnina Nadezhda Alisultanova Lubov Kalikova Anastasia Tretyakova Alexey Chernykh Vera Shadrina Arina Duryagina Evgeny Bojko |
| author_sort | Natalya Potolitsyna |
| collection | DOAJ |
| description | Abstract The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (Tex) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion without a load or with a load of 2%–10% of body weight (BW). In the first group, we established that for untrained rats, the load of 4% BW in the swimming to exhaustion test was optimal for endurance assessment in comparison with other loads. The second group of rats went through a preliminary test with swimming to exhaustion at 4% BW and was then divided into two subgroups: long swimming time (LST, Tex > 240 min) and short swimming time (SST, Tex < 90 min). All rats of the second group performed, for 6 days, an experimental training protocol: swimming for 20 min each day with weight increasing each day. We established that the AT was 3% BW in SST rats and 5% BW in LST rats. The AT shifted to the right on the lactate curve in LST rats. Also, at the AT in the LST rats, we found significantly lower levels of blood lactate, cortisol, and NO. |
| first_indexed | 2024-03-08T16:42:23Z |
| format | Article |
| id | doaj.art-aea34bc2f1444e2fb8ff7d24e7c71c60 |
| institution | Directory Open Access Journal |
| issn | 2051-817X |
| language | English |
| last_indexed | 2024-03-08T16:42:23Z |
| publishDate | 2023-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Physiological Reports |
| spelling | doaj.art-aea34bc2f1444e2fb8ff7d24e7c71c602024-01-05T09:46:30ZengWileyPhysiological Reports2051-817X2023-09-011117n/an/a10.14814/phy2.15801Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustionNatalya Potolitsyna0Olga Parshukova1Nadezhda Vakhnina2Nadezhda Alisultanova3Lubov Kalikova4Anastasia Tretyakova5Alexey Chernykh6Vera Shadrina7Arina Duryagina8Evgeny Bojko9Institute of Physiology of Kоmi Science Centre of the Ural Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS Syktyvkar RussiaInstitute of Physiology of Kоmi Science Centre of the Ural Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS Syktyvkar RussiaInstitute of Physiology of Kоmi Science Centre of the Ural Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS Syktyvkar RussiaInstitute of Physiology of Kоmi Science Centre of the Ural Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS Syktyvkar RussiaInstitute of Physiology of Kоmi Science Centre of the Ural Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS Syktyvkar RussiaInstitute of Physiology of Kоmi Science Centre of the Ural Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS Syktyvkar RussiaInstitute of Physiology of Kоmi Science Centre of the Ural Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS Syktyvkar RussiaInstitute of Physiology of Kоmi Science Centre of the Ural Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS Syktyvkar RussiaInstitute of Physiology of Kоmi Science Centre of the Ural Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS Syktyvkar RussiaInstitute of Physiology of Kоmi Science Centre of the Ural Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS Syktyvkar RussiaAbstract The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (Tex) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion without a load or with a load of 2%–10% of body weight (BW). In the first group, we established that for untrained rats, the load of 4% BW in the swimming to exhaustion test was optimal for endurance assessment in comparison with other loads. The second group of rats went through a preliminary test with swimming to exhaustion at 4% BW and was then divided into two subgroups: long swimming time (LST, Tex > 240 min) and short swimming time (SST, Tex < 90 min). All rats of the second group performed, for 6 days, an experimental training protocol: swimming for 20 min each day with weight increasing each day. We established that the AT was 3% BW in SST rats and 5% BW in LST rats. The AT shifted to the right on the lactate curve in LST rats. Also, at the AT in the LST rats, we found significantly lower levels of blood lactate, cortisol, and NO.https://doi.org/10.14814/phy2.15801anaerobic thresholdexhaustionlactate biochemical indicesratsswimming test |
| spellingShingle | Natalya Potolitsyna Olga Parshukova Nadezhda Vakhnina Nadezhda Alisultanova Lubov Kalikova Anastasia Tretyakova Alexey Chernykh Vera Shadrina Arina Duryagina Evgeny Bojko Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion Physiological Reports anaerobic threshold exhaustion lactate biochemical indices rats swimming test |
| title | Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion |
| title_full | Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion |
| title_fullStr | Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion |
| title_full_unstemmed | Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion |
| title_short | Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion |
| title_sort | lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion |
| topic | anaerobic threshold exhaustion lactate biochemical indices rats swimming test |
| url | https://doi.org/10.14814/phy2.15801 |
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