Barriers to management of opioid withdrawal in hospitals in England: a document analysis of hospital policies on the management of substance dependence

Abstract Background People who use illicit opioids are more likely to be admitted to hospital than people of the same age in the general population. Many admissions end in discharge against medical advice, which is associated with readmission and all-cause mortality. Opioid withdrawal contributes to...

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Main Authors: Magdalena Harris, Adam Holland, Dan Lewer, Michael Brown, Niamh Eastwood, Gary Sutton, Ben Sansom, Gabby Cruickshank, Molly Bradbury, Isabelle Guest, Jenny Scott
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12916-022-02351-y
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author Magdalena Harris
Adam Holland
Dan Lewer
Michael Brown
Niamh Eastwood
Gary Sutton
Ben Sansom
Gabby Cruickshank
Molly Bradbury
Isabelle Guest
Jenny Scott
author_facet Magdalena Harris
Adam Holland
Dan Lewer
Michael Brown
Niamh Eastwood
Gary Sutton
Ben Sansom
Gabby Cruickshank
Molly Bradbury
Isabelle Guest
Jenny Scott
author_sort Magdalena Harris
collection DOAJ
description Abstract Background People who use illicit opioids are more likely to be admitted to hospital than people of the same age in the general population. Many admissions end in discharge against medical advice, which is associated with readmission and all-cause mortality. Opioid withdrawal contributes to premature discharge. We sought to understand the barriers to timely provision of opioid substitution therapy (OST), which helps to prevent opioid withdrawal, in acute hospitals in England. Methods We requested policies on substance dependence management from 135 National Health Service trusts, which manage acute hospitals in England, and conducted a document content analysis. Additionally, we reviewed an Omitted and Delayed Medicines Tool (ODMT), one resource used to inform critical medicine categorisation in England. We worked closely with people with lived experience of OST and/or illicit opioid use, informed by principles of community-based participatory research. Results Eighty-six (64%) trusts provided 101 relevant policies. An additional 44 (33%) responded but could not provide relevant policies, and five (4%) did not send a definitive response. Policies illustrate procedural barriers to OST provision, including inconsistent application of national guidelines across trusts. Continuing community OST prescriptions for people admitted in the evening, night-time, or weekend was often precluded by requirements to confirm doses with organisations that were closed during these hours. 42/101 trusts (42%) required or recommended a urine drug test positive for OST medications or opioids prior to OST prescription. The language used in many policies was stigmatising and characterised people who use drugs as untrustworthy. OST was not specifically mentioned in the reviewed ODMT, with ‘drugs used in substance dependence’ collectively categorised as posing low risk if delayed and moderate risk if omitted. Conclusions Many hospitals in England have policies that likely prevent timely and effective OST. This was underpinned by the ‘low-risk’ categorisation of OST delay in the ODMT. Delays to continuity of OST between community and hospital settings may contribute to inpatient opioid withdrawal and increase the risk of discharge against medical advice. Acute hospitals in England require standardised best practice policies that account for the needs of this patient group.
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spelling doaj.art-aea4521b51ef4e4d895da61d6c5f88bb2022-12-22T02:56:33ZengBMCBMC Medicine1741-70152022-04-0120111110.1186/s12916-022-02351-yBarriers to management of opioid withdrawal in hospitals in England: a document analysis of hospital policies on the management of substance dependenceMagdalena Harris0Adam Holland1Dan Lewer2Michael Brown3Niamh Eastwood4Gary Sutton5Ben Sansom6Gabby Cruickshank7Molly Bradbury8Isabelle Guest9Jenny Scott10Department of Public Health, Environments and Society, London School of Hygiene and Tropical MedicineDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical MedicineDepartment of Epidemiology and Public Health, University College LondonDivision of Infection, University College London HospitalReleaseReleaseBristol Medical School, University of BristolBristol Medical School, University of BristolSevern Foundation SchoolSouthmead HospitalDepartment of Pharmacy & Pharmacology, University of BathAbstract Background People who use illicit opioids are more likely to be admitted to hospital than people of the same age in the general population. Many admissions end in discharge against medical advice, which is associated with readmission and all-cause mortality. Opioid withdrawal contributes to premature discharge. We sought to understand the barriers to timely provision of opioid substitution therapy (OST), which helps to prevent opioid withdrawal, in acute hospitals in England. Methods We requested policies on substance dependence management from 135 National Health Service trusts, which manage acute hospitals in England, and conducted a document content analysis. Additionally, we reviewed an Omitted and Delayed Medicines Tool (ODMT), one resource used to inform critical medicine categorisation in England. We worked closely with people with lived experience of OST and/or illicit opioid use, informed by principles of community-based participatory research. Results Eighty-six (64%) trusts provided 101 relevant policies. An additional 44 (33%) responded but could not provide relevant policies, and five (4%) did not send a definitive response. Policies illustrate procedural barriers to OST provision, including inconsistent application of national guidelines across trusts. Continuing community OST prescriptions for people admitted in the evening, night-time, or weekend was often precluded by requirements to confirm doses with organisations that were closed during these hours. 42/101 trusts (42%) required or recommended a urine drug test positive for OST medications or opioids prior to OST prescription. The language used in many policies was stigmatising and characterised people who use drugs as untrustworthy. OST was not specifically mentioned in the reviewed ODMT, with ‘drugs used in substance dependence’ collectively categorised as posing low risk if delayed and moderate risk if omitted. Conclusions Many hospitals in England have policies that likely prevent timely and effective OST. This was underpinned by the ‘low-risk’ categorisation of OST delay in the ODMT. Delays to continuity of OST between community and hospital settings may contribute to inpatient opioid withdrawal and increase the risk of discharge against medical advice. Acute hospitals in England require standardised best practice policies that account for the needs of this patient group.https://doi.org/10.1186/s12916-022-02351-yOpioid substitution therapyOpioid dependenceOpioid withdrawalHospital policyPeople who use drugsDischarge against medical advice
spellingShingle Magdalena Harris
Adam Holland
Dan Lewer
Michael Brown
Niamh Eastwood
Gary Sutton
Ben Sansom
Gabby Cruickshank
Molly Bradbury
Isabelle Guest
Jenny Scott
Barriers to management of opioid withdrawal in hospitals in England: a document analysis of hospital policies on the management of substance dependence
BMC Medicine
Opioid substitution therapy
Opioid dependence
Opioid withdrawal
Hospital policy
People who use drugs
Discharge against medical advice
title Barriers to management of opioid withdrawal in hospitals in England: a document analysis of hospital policies on the management of substance dependence
title_full Barriers to management of opioid withdrawal in hospitals in England: a document analysis of hospital policies on the management of substance dependence
title_fullStr Barriers to management of opioid withdrawal in hospitals in England: a document analysis of hospital policies on the management of substance dependence
title_full_unstemmed Barriers to management of opioid withdrawal in hospitals in England: a document analysis of hospital policies on the management of substance dependence
title_short Barriers to management of opioid withdrawal in hospitals in England: a document analysis of hospital policies on the management of substance dependence
title_sort barriers to management of opioid withdrawal in hospitals in england a document analysis of hospital policies on the management of substance dependence
topic Opioid substitution therapy
Opioid dependence
Opioid withdrawal
Hospital policy
People who use drugs
Discharge against medical advice
url https://doi.org/10.1186/s12916-022-02351-y
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