A rational approach to the treatment of hepatic encephalopathy in patients with liver cirrhosis

In 125 patients with liver cirrhosis of different etiologies, classes A, B and C according to the Child-Pugh, with minimal hepatic encephalopathy and overt encephalopathy to II grade according to the West Haven criteria, we studied the efficacy of treatment of hepatic encephalopathy drugs of differe...

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Main Authors: K. V. Zhdanov, D. A. Gusev, S. M. Zakharenko, M. V. Kurtukov, K. V. Kozlov, V. S. Sukachev, A. S. Sigidaev, M. S. Talantseva
Format: Article
Language:Russian
Published: Journal Infectology 2014-09-01
Series:Журнал инфектологии
Subjects:
Online Access:https://journal.niidi.ru/jofin/article/view/130
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author K. V. Zhdanov
D. A. Gusev
S. M. Zakharenko
M. V. Kurtukov
K. V. Kozlov
V. S. Sukachev
A. S. Sigidaev
M. S. Talantseva
author_facet K. V. Zhdanov
D. A. Gusev
S. M. Zakharenko
M. V. Kurtukov
K. V. Kozlov
V. S. Sukachev
A. S. Sigidaev
M. S. Talantseva
author_sort K. V. Zhdanov
collection DOAJ
description In 125 patients with liver cirrhosis of different etiologies, classes A, B and C according to the Child-Pugh, with minimal hepatic encephalopathy and overt encephalopathy to II grade according to the West Haven criteria, we studied the efficacy of treatment of hepatic encephalopathy drugs of different pharmacological groups. The highest efficiency was found in the treatment with Stimol, treatment with probiotics and treatment included the combination of probiotics with metronidazole. Treatment with these drugs showed improvement in clinical status and in psychometric (cognitive) performance, as well as positive changes in clinical and biochemical parameters of blood. Also, this treatment was associated with the improving the quality of life of patients.
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spelling doaj.art-aeab4fb598024c0daac4419514f4ef042023-08-02T07:52:22ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-0144324110.22625/2072-6732-2012-4-4-32-41144A rational approach to the treatment of hepatic encephalopathy in patients with liver cirrhosisK. V. Zhdanov0D. A. Gusev1S. M. Zakharenko2M. V. Kurtukov3K. V. Kozlov4V. S. Sukachev5A. S. Sigidaev6M. S. Talantseva7Военно-медицинская академия имени С.М. Кирова, Санкт-ПетербургВоенно-медицинская академия имени С.М. Кирова, Санкт-ПетербургВоенно-медицинская академия имени С.М. Кирова, Санкт-ПетербургВоенно-медицинская академия имени С.М. Кирова, Санкт-ПетербургВоенно-медицинская академия имени С.М. Кирова, Санкт-ПетербургВоенно-медицинская академия имени С.М. Кирова, Санкт-ПетербургВоенно-медицинская академия имени С.М. Кирова, Санкт-ПетербургВоенно-медицинская академия имени С.М. Кирова, Санкт-ПетербургIn 125 patients with liver cirrhosis of different etiologies, classes A, B and C according to the Child-Pugh, with minimal hepatic encephalopathy and overt encephalopathy to II grade according to the West Haven criteria, we studied the efficacy of treatment of hepatic encephalopathy drugs of different pharmacological groups. The highest efficiency was found in the treatment with Stimol, treatment with probiotics and treatment included the combination of probiotics with metronidazole. Treatment with these drugs showed improvement in clinical status and in psychometric (cognitive) performance, as well as positive changes in clinical and biochemical parameters of blood. Also, this treatment was associated with the improving the quality of life of patients.https://journal.niidi.ru/jofin/article/view/130цирроз печенипеченочная энцефалопатиястимол (цитруллина малат)метронидазолпробиотики
spellingShingle K. V. Zhdanov
D. A. Gusev
S. M. Zakharenko
M. V. Kurtukov
K. V. Kozlov
V. S. Sukachev
A. S. Sigidaev
M. S. Talantseva
A rational approach to the treatment of hepatic encephalopathy in patients with liver cirrhosis
Журнал инфектологии
цирроз печени
печеночная энцефалопатия
стимол (цитруллина малат)
метронидазол
пробиотики
title A rational approach to the treatment of hepatic encephalopathy in patients with liver cirrhosis
title_full A rational approach to the treatment of hepatic encephalopathy in patients with liver cirrhosis
title_fullStr A rational approach to the treatment of hepatic encephalopathy in patients with liver cirrhosis
title_full_unstemmed A rational approach to the treatment of hepatic encephalopathy in patients with liver cirrhosis
title_short A rational approach to the treatment of hepatic encephalopathy in patients with liver cirrhosis
title_sort rational approach to the treatment of hepatic encephalopathy in patients with liver cirrhosis
topic цирроз печени
печеночная энцефалопатия
стимол (цитруллина малат)
метронидазол
пробиотики
url https://journal.niidi.ru/jofin/article/view/130
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