Adjuvant transcranial direct current stimulation for treating Alzheimer's disease: A case study

ABSTRACT We report the case of a 73-year-old male patient with Alzheimer's disease who underwent 10-daily transcranial direct current stimulation (tDCS) sessions. tDCS was applied over the left dorsolateral prefrontal cortex as an adjuvant to the traditional treatment that the patient was recei...

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Main Authors: Suellen Marinho Andrade, Camila Teresa Ponce Leon de Mendonça, Thobias Cavalcanti Laurindo Pereira, Bernardino Fernandez-Calvo, Regina Coely Neves Araújo, Nelson Torro Alves
Format: Article
Language:English
Published: Associação Neurologia Cognitiva e do Comportamento
Series:Dementia & Neuropsychologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642016000200156&lng=en&tlng=en
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author Suellen Marinho Andrade
Camila Teresa Ponce Leon de Mendonça
Thobias Cavalcanti Laurindo Pereira
Bernardino Fernandez-Calvo
Regina Coely Neves Araújo
Nelson Torro Alves
author_facet Suellen Marinho Andrade
Camila Teresa Ponce Leon de Mendonça
Thobias Cavalcanti Laurindo Pereira
Bernardino Fernandez-Calvo
Regina Coely Neves Araújo
Nelson Torro Alves
author_sort Suellen Marinho Andrade
collection DOAJ
description ABSTRACT We report the case of a 73-year-old male patient with Alzheimer's disease who underwent 10-daily transcranial direct current stimulation (tDCS) sessions. tDCS was applied over the left dorsolateral prefrontal cortex as an adjuvant to the traditional treatment that the patient was receiving, which consisted of anticholinergic medication and cognitive training. The data were qualitatively analyzed and are presented in an analytic and structured form. The effects on cognitive performance were evaluated using the Alzheimer's Disease Assessment Scale-cognitive subscale as the primary outcome. Secondary outcomes were assessed with a set of tests consisting of the Neuropsychiatric Inventory, the Blessed Dementia Scale and the Disability Assessment for Dementia. The data obtained revealed that the application of tDCS had a stabilizing effect on overall patient cognitive function and led to improved performance on all the secondary outcome tests. These preliminary results indicate that tDCS is a potential adjuvant therapeutic tool for cognitive rehabilitation in Alzheimer's disease .
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spelling doaj.art-aeac6bc7fe8944a5bbed3a86809eeade2022-12-22T02:45:43ZengAssociação Neurologia Cognitiva e do ComportamentoDementia & Neuropsychologia1980-576410215615910.1590/S1980-5764-2016DN1002013S1980-57642016000200156Adjuvant transcranial direct current stimulation for treating Alzheimer's disease: A case studySuellen Marinho AndradeCamila Teresa Ponce Leon de MendonçaThobias Cavalcanti Laurindo PereiraBernardino Fernandez-CalvoRegina Coely Neves AraújoNelson Torro AlvesABSTRACT We report the case of a 73-year-old male patient with Alzheimer's disease who underwent 10-daily transcranial direct current stimulation (tDCS) sessions. tDCS was applied over the left dorsolateral prefrontal cortex as an adjuvant to the traditional treatment that the patient was receiving, which consisted of anticholinergic medication and cognitive training. The data were qualitatively analyzed and are presented in an analytic and structured form. The effects on cognitive performance were evaluated using the Alzheimer's Disease Assessment Scale-cognitive subscale as the primary outcome. Secondary outcomes were assessed with a set of tests consisting of the Neuropsychiatric Inventory, the Blessed Dementia Scale and the Disability Assessment for Dementia. The data obtained revealed that the application of tDCS had a stabilizing effect on overall patient cognitive function and led to improved performance on all the secondary outcome tests. These preliminary results indicate that tDCS is a potential adjuvant therapeutic tool for cognitive rehabilitation in Alzheimer's disease .http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642016000200156&lng=en&tlng=enelectrical stimulationdementiaAlzheimer's diseasecognitive therapy
spellingShingle Suellen Marinho Andrade
Camila Teresa Ponce Leon de Mendonça
Thobias Cavalcanti Laurindo Pereira
Bernardino Fernandez-Calvo
Regina Coely Neves Araújo
Nelson Torro Alves
Adjuvant transcranial direct current stimulation for treating Alzheimer's disease: A case study
Dementia & Neuropsychologia
electrical stimulation
dementia
Alzheimer's disease
cognitive therapy
title Adjuvant transcranial direct current stimulation for treating Alzheimer's disease: A case study
title_full Adjuvant transcranial direct current stimulation for treating Alzheimer's disease: A case study
title_fullStr Adjuvant transcranial direct current stimulation for treating Alzheimer's disease: A case study
title_full_unstemmed Adjuvant transcranial direct current stimulation for treating Alzheimer's disease: A case study
title_short Adjuvant transcranial direct current stimulation for treating Alzheimer's disease: A case study
title_sort adjuvant transcranial direct current stimulation for treating alzheimer s disease a case study
topic electrical stimulation
dementia
Alzheimer's disease
cognitive therapy
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642016000200156&lng=en&tlng=en
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