Macroglossia and less advanced dystrophic change in the tongue muscle of the Duchenne muscular dystrophy rat

Abstract Background Duchenne muscular dystrophy (DMD) is an X-linked muscle disease caused by a complete lack of dystrophin, which stabilizes the plasma membrane of myofibers. The orofacial function is affected in an advanced stage of DMD and this often leads to an eating disorder such as dysphagia....

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Main Authors: Keitaro Yamanouchi, Yukie Tanaka, Masanari Ikeda, Shizuka Kato, Ryosuke Okino, Hiroki Nishi, Fumihiko Hakuno, Shin-Ichiro Takahashi, James Chambers, Takashi Matsuwaki, Kazuyuki Uchida
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Skeletal Muscle
Subjects:
Online Access:https://doi.org/10.1186/s13395-022-00307-7