The Transcriptional Landscape of Marek’s Disease Virus in Primary Chicken B Cells Reveals Novel Splice Variants and Genes

The Transcriptional Landscape of Marek’s Disease Virus in Primary Chicken B Cells Reveals Novel Splice Variants and Genes

Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that infects chickens and poses a serious threat to poultry health. In infected animals, MDV efficiently replicates in B cells in various lymphoid organs. Despite many years of research, the viral transcriptome in primary target...

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Bibliographic Details
Main Authors: Luca D. Bertzbach, Florian Pfaff, Viktoria I. Pauker, Ahmed M. Kheimar, Dirk Höper, Sonja Härtle, Axel Karger, Benedikt B. Kaufer
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Viruses
Subjects:
Marek’s disease virus (MDV)
RNA-seq
transcriptome
splicing
polycistronic viral transcripts
primary B cells
RB1B
CVI988/Rispens
ICP0
Online Access:http://www.mdpi.com/1999-4915/11/3/264

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