Efficacy of non-invasive high frequency oscillatory ventilation as post-extubation respiratory support in preterm neonates: a randomized controlled trial
Objective To compare the efficacy of non-invasive high-frequency oscillatory ventilation (NHFOV) with nasal continuous positive airway pressure (NCPAP) in preterm infants aged 26+0~31+6 weeks as post-extubation respiratory support. Methods A total of 114 infants admitted to Department of Neonatology...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Third Military Medical University
2019-09-01
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| Series: | Di-san junyi daxue xuebao |
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| Online Access: | http://aammt.tmmu.edu.cn/Upload/rhtml/201903161.htm |
| _version_ | 1818407435956649984 |
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| author | LI Huanhuan LI Huanhuan ZHU Xingwang WANG Wanjun |
| author_facet | LI Huanhuan LI Huanhuan ZHU Xingwang WANG Wanjun |
| author_sort | LI Huanhuan |
| collection | DOAJ |
| description | Objective To compare the efficacy of non-invasive high-frequency oscillatory ventilation (NHFOV) with nasal continuous positive airway pressure (NCPAP) in preterm infants aged 26+0~31+6 weeks as post-extubation respiratory support. Methods A total of 114 infants admitted to Department of Neonatology, Jiulongpo District People's Hospital and Diagnosis and Treatment Center for Neonates of Children's Hospital of Chongqing Medical University during January 2017 to January 2019 were recruited, and randomized to NCPAP group (n=58, control) and NHFOV group (n=56) by envelope extraction. The primary outcomes were treatment failure and need for re-intubation within 7 d after extubation. Secondary outcomes included duration of noninvasive ventilation, length of hospitalization, mortality, and incidences of pneumothorax, bronchopulmonary dysplasia (BPD) at 36 weeks of postmenstrual age or discharge, intracranial hemorrhage (IVH) and necrotizing enterocolitis (NEC). Results The rate of treatment failure and need for re-intubation within 7 d after extubation was significantly lower in the NHFOV group than the NCPAP group (14.2% vs 31.0%, P=0.033). There were no statistically differences in all other secondary outcomes between the 2 groups. Conclusion NHFOV can improve the success rate of weaning and reduce the need for re-intubation as compared with NCPAP in preterm infants after extubation. |
| first_indexed | 2024-12-14T09:27:48Z |
| format | Article |
| id | doaj.art-aeb69f6e953a49e0a6817927603d87ed |
| institution | Directory Open Access Journal |
| issn | 1000-5404 |
| language | zho |
| last_indexed | 2024-12-14T09:27:48Z |
| publishDate | 2019-09-01 |
| publisher | Editorial Office of Journal of Third Military Medical University |
| record_format | Article |
| series | Di-san junyi daxue xuebao |
| spelling | doaj.art-aeb69f6e953a49e0a6817927603d87ed2022-12-21T23:08:09ZzhoEditorial Office of Journal of Third Military Medical UniversityDi-san junyi daxue xuebao1000-54042019-09-0141171688169210.16016/j.1000-5404.201903161Efficacy of non-invasive high frequency oscillatory ventilation as post-extubation respiratory support in preterm neonates: a randomized controlled trialLI Huanhuan0LI Huanhuan1 ZHU Xingwang2WANG Wanjun3Department of Neonatology, Jiulongpo District People's Hospital, Chongqing, 400000Diagnosis and Treatment Center for Neonates, Children's Hospital of Chongqing Medical University, Chongqing, 400014, ChinaDepartment of Neonatology, Jiulongpo District People's Hospital, Chongqing, 400000Department of Neonatology, Jiulongpo District People's Hospital, Chongqing, 400000Objective To compare the efficacy of non-invasive high-frequency oscillatory ventilation (NHFOV) with nasal continuous positive airway pressure (NCPAP) in preterm infants aged 26+0~31+6 weeks as post-extubation respiratory support. Methods A total of 114 infants admitted to Department of Neonatology, Jiulongpo District People's Hospital and Diagnosis and Treatment Center for Neonates of Children's Hospital of Chongqing Medical University during January 2017 to January 2019 were recruited, and randomized to NCPAP group (n=58, control) and NHFOV group (n=56) by envelope extraction. The primary outcomes were treatment failure and need for re-intubation within 7 d after extubation. Secondary outcomes included duration of noninvasive ventilation, length of hospitalization, mortality, and incidences of pneumothorax, bronchopulmonary dysplasia (BPD) at 36 weeks of postmenstrual age or discharge, intracranial hemorrhage (IVH) and necrotizing enterocolitis (NEC). Results The rate of treatment failure and need for re-intubation within 7 d after extubation was significantly lower in the NHFOV group than the NCPAP group (14.2% vs 31.0%, P=0.033). There were no statistically differences in all other secondary outcomes between the 2 groups. Conclusion NHFOV can improve the success rate of weaning and reduce the need for re-intubation as compared with NCPAP in preterm infants after extubation.http://aammt.tmmu.edu.cn/Upload/rhtml/201903161.htmpreterm infantsnon-invasive high-frequency oscillatory ventilationnasal continuous positive airway pressure |
| spellingShingle | LI Huanhuan LI Huanhuan ZHU Xingwang WANG Wanjun Efficacy of non-invasive high frequency oscillatory ventilation as post-extubation respiratory support in preterm neonates: a randomized controlled trial Di-san junyi daxue xuebao preterm infants non-invasive high-frequency oscillatory ventilation nasal continuous positive airway pressure |
| title | Efficacy of non-invasive high frequency oscillatory ventilation as post-extubation respiratory support in preterm neonates: a randomized controlled trial |
| title_full | Efficacy of non-invasive high frequency oscillatory ventilation as post-extubation respiratory support in preterm neonates: a randomized controlled trial |
| title_fullStr | Efficacy of non-invasive high frequency oscillatory ventilation as post-extubation respiratory support in preterm neonates: a randomized controlled trial |
| title_full_unstemmed | Efficacy of non-invasive high frequency oscillatory ventilation as post-extubation respiratory support in preterm neonates: a randomized controlled trial |
| title_short | Efficacy of non-invasive high frequency oscillatory ventilation as post-extubation respiratory support in preterm neonates: a randomized controlled trial |
| title_sort | efficacy of non invasive high frequency oscillatory ventilation as post extubation respiratory support in preterm neonates a randomized controlled trial |
| topic | preterm infants non-invasive high-frequency oscillatory ventilation nasal continuous positive airway pressure |
| url | http://aammt.tmmu.edu.cn/Upload/rhtml/201903161.htm |
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