Association of Bone Mineral Density with Albuminuria and Estimated Glomerular Filtration Rate : The Dong-gu Study
Background: Kidney dysfunction and albuminuria may be associated with BMD. However, little evidence has been reported on relationships between BMD and eGFR and albuminuria. Methods: A total of 8,992 subjects aged 50 years or older participated in a survey conducted. Participants had their lumbar spi...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2013-04-01
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| Series: | Kidney & Blood Pressure Research |
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| Online Access: | http://www.karger.com/Article/FullText/350067 |
| _version_ | 1818441702180913152 |
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| author | Seong-Woo Choi Hye-Yeon Kim Hye-Ran Ahn Young-Hoon Lee Sun-Seog Kweon Jin-Su Choi Jung-Ae Rhee Hae-Sung Nam Seul-Ki Jeong Kyeong-Soo Park So-Yeon Ryu Hye-Rim Song Min-Ho Shin |
| author_facet | Seong-Woo Choi Hye-Yeon Kim Hye-Ran Ahn Young-Hoon Lee Sun-Seog Kweon Jin-Su Choi Jung-Ae Rhee Hae-Sung Nam Seul-Ki Jeong Kyeong-Soo Park So-Yeon Ryu Hye-Rim Song Min-Ho Shin |
| author_sort | Seong-Woo Choi |
| collection | DOAJ |
| description | Background: Kidney dysfunction and albuminuria may be associated with BMD. However, little evidence has been reported on relationships between BMD and eGFR and albuminuria. Methods: A total of 8,992 subjects aged 50 years or older participated in a survey conducted. Participants had their lumbar spine and femoral neck BMD measured by a Lunar Prodigy bone densitometer (GE, Madison, WI). Kidney function was assessed using MDRD eGFR and diagnosis of albuminuria was based on albumin-creatinine ratio. Results: ACR was negatively associated with lumbar spine and femur neck BMD in females (lumbar spine: 1.001, 0.988, 0.974 and 0.979 g/cm2, p 2, p = 0.002), but not in males, after adjusting for covariates. Additionally, eGFR was shown to be negatively associated with lumbar spine BMD after adjusting for covariates (male: 1.181, 1.166, 1.152 and 1.149 g/cm2, p = 0.001; female: 0.997, 0.980, 0.979 and 0.982 g/cm2, p = 0.005), but demonstrated no association with femur BMD. Conclusions: ACR in females was negatively associated with lumbar spine and femur neck BMD, but not in males. eGFR was negatively associated with lumbar spine BMD in both males and females. |
| first_indexed | 2024-12-14T18:32:27Z |
| format | Article |
| id | doaj.art-aeb869bfead641c7a23eacb611e5f7eb |
| institution | Directory Open Access Journal |
| issn | 1420-4096 1423-0143 |
| language | English |
| last_indexed | 2024-12-14T18:32:27Z |
| publishDate | 2013-04-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Kidney & Blood Pressure Research |
| spelling | doaj.art-aeb869bfead641c7a23eacb611e5f7eb2022-12-21T22:51:44ZengKarger PublishersKidney & Blood Pressure Research1420-40961423-01432013-04-01372-313214110.1159/000350067350067Association of Bone Mineral Density with Albuminuria and Estimated Glomerular Filtration Rate : The Dong-gu StudySeong-Woo ChoiHye-Yeon KimHye-Ran AhnYoung-Hoon LeeSun-Seog KweonJin-Su ChoiJung-Ae RheeHae-Sung NamSeul-Ki JeongKyeong-Soo ParkSo-Yeon RyuHye-Rim SongMin-Ho ShinBackground: Kidney dysfunction and albuminuria may be associated with BMD. However, little evidence has been reported on relationships between BMD and eGFR and albuminuria. Methods: A total of 8,992 subjects aged 50 years or older participated in a survey conducted. Participants had their lumbar spine and femoral neck BMD measured by a Lunar Prodigy bone densitometer (GE, Madison, WI). Kidney function was assessed using MDRD eGFR and diagnosis of albuminuria was based on albumin-creatinine ratio. Results: ACR was negatively associated with lumbar spine and femur neck BMD in females (lumbar spine: 1.001, 0.988, 0.974 and 0.979 g/cm2, p 2, p = 0.002), but not in males, after adjusting for covariates. Additionally, eGFR was shown to be negatively associated with lumbar spine BMD after adjusting for covariates (male: 1.181, 1.166, 1.152 and 1.149 g/cm2, p = 0.001; female: 0.997, 0.980, 0.979 and 0.982 g/cm2, p = 0.005), but demonstrated no association with femur BMD. Conclusions: ACR in females was negatively associated with lumbar spine and femur neck BMD, but not in males. eGFR was negatively associated with lumbar spine BMD in both males and females.http://www.karger.com/Article/FullText/350067Bone mineral denstiyAlbuminuriaEstimated glomerular filtration rate |
| spellingShingle | Seong-Woo Choi Hye-Yeon Kim Hye-Ran Ahn Young-Hoon Lee Sun-Seog Kweon Jin-Su Choi Jung-Ae Rhee Hae-Sung Nam Seul-Ki Jeong Kyeong-Soo Park So-Yeon Ryu Hye-Rim Song Min-Ho Shin Association of Bone Mineral Density with Albuminuria and Estimated Glomerular Filtration Rate : The Dong-gu Study Kidney & Blood Pressure Research Bone mineral denstiy Albuminuria Estimated glomerular filtration rate |
| title | Association of Bone Mineral Density with Albuminuria and Estimated Glomerular Filtration Rate : The Dong-gu Study |
| title_full | Association of Bone Mineral Density with Albuminuria and Estimated Glomerular Filtration Rate : The Dong-gu Study |
| title_fullStr | Association of Bone Mineral Density with Albuminuria and Estimated Glomerular Filtration Rate : The Dong-gu Study |
| title_full_unstemmed | Association of Bone Mineral Density with Albuminuria and Estimated Glomerular Filtration Rate : The Dong-gu Study |
| title_short | Association of Bone Mineral Density with Albuminuria and Estimated Glomerular Filtration Rate : The Dong-gu Study |
| title_sort | association of bone mineral density with albuminuria and estimated glomerular filtration rate the dong gu study |
| topic | Bone mineral denstiy Albuminuria Estimated glomerular filtration rate |
| url | http://www.karger.com/Article/FullText/350067 |
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