The viral KSHV chemokine vMIP-II inhibits the migration of Naive and activated human NK cells by antagonizing two distinct chemokine receptors.

The viral KSHV chemokine vMIP-II inhibits the migration of Naive and activated human NK cells by antagonizing two distinct chemokine receptors.

Natural killer (NK) cells are innate immune cells able to rapidly kill virus-infected and tumor cells. Two NK cell populations are found in the blood; the majority (90%) expresses the CD16 receptor and also express the CD56 protein in intermediate levels (CD56(Dim) CD16(Pos)) while the remaining 10%...

Full description

Bibliographic Details
Main Authors: Rachel Yamin, Noa S Kaynan, Ariella Glasner, Alon Vitenshtein, Pinchas Tsukerman, Yoav Bauman, Yael Ophir, Shlomo Elias, Yotam Bar-On, Chamutal Gur, Ofer Mandelboim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3744409?pdf=render

Similar Items

Similar Items