Optimisation of the Manufacturing Process of Organic-Solvent-Free Omeprazole Enteric Pellets for the Paediatric Population: Full Factorial Design

Optimisation of the Manufacturing Process of Organic-Solvent-Free Omeprazole Enteric Pellets for the Paediatric Population: Full Factorial Design

Liquid formulations are mostly used in the paediatric population. However, with certain active pharmaceutical ingredients (APIs), it is very difficult to guarantee quality and stability; this is the case, for example, with omeprazole. Omeprazole is used as a model drug due to the lack of a paediatri...

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Bibliographic Details
Main Authors: Khadija Rouaz-El-Hajoui, Encarnación García-Montoya, Andrea López-Urbano, Miquel Romero-Obon, Blanca Chiclana-Rodríguez, Alex Fraschi-Nieto, Anna Nardi-Ricart, Marc Suñé-Pou, Josep María Suñé-Negre, Pilar Pérez-Lozano
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceutics
Subjects:
omeprazole
pellets
enteric coating
design of experiments and paediatric population
Online Access:https://www.mdpi.com/1999-4923/15/11/2587

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https://www.mdpi.com/1999-4923/15/11/2587

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