The study of a novel sorafenib derivative HLC-080 as an antitumor agent.

In this study, our objective is to evaluate the potential of a novel Sorafenib derivative, named HLC-080, as a new anticancer agent for colon cancer. We firstly carried out MTT assay, colony formation assay, flow cytometry analysis and transwell invasion assay to determine effect of our compound HLC...

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Bibliographic Details
Main Authors: Ke Tang, Can Luo, Yan Li, Chenshu Lu, Wanqi Zhou, Haihong Huang, Xiaoguang Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4086976?pdf=render