Analysis on the Risk Factors of Malnutrition in Type 2 Diabetes Mellitus Patients with Pulmonary Tuberculosis
Liangliang Ma,1 Xuelin Chen,1 Maolong Gao2 1Department of Infectious Diseases, Beijing Geriatric Hospital, Beijing, 100095, People’s Republic of China; 2Department of Science and Technology, Beijing Geriatric Hospital, Beijing, 100095, People’s Republic of ChinaCorrespondence: Liangliang Ma, Departm...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2022-12-01
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| Series: | Infection and Drug Resistance |
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| Online Access: | https://www.dovepress.com/analysis-on-the-risk-factors-of-malnutrition-in-type-2-diabetes-mellit-peer-reviewed-fulltext-article-IDR |
| _version_ | 1797979760429629440 |
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| author | Ma L Chen X Gao M |
| author_facet | Ma L Chen X Gao M |
| author_sort | Ma L |
| collection | DOAJ |
| description | Liangliang Ma,1 Xuelin Chen,1 Maolong Gao2 1Department of Infectious Diseases, Beijing Geriatric Hospital, Beijing, 100095, People’s Republic of China; 2Department of Science and Technology, Beijing Geriatric Hospital, Beijing, 100095, People’s Republic of ChinaCorrespondence: Liangliang Ma, Department of Infectious Diseases, Beijing Geriatric Hospital, No. 118 Wenquan Road, Haidian District, Beijing, 100095, People’s Republic of China, Tel +86-18610672953, Email gkdp29@163.comObjective: To explore the risk factors of malnutrition in type 2 diabetes mellitus combined with pulmonary tuberculosis (PTB-T2DM) patients and further to provide a clinical research basis for the identification and prevention of malnutrition.Methods: From January 2020 to February 2022, 307 adult patients diagnosed with PTB-T2DM were enrolled in this retrospective study. According to whether malnutrition occurred after 6 months of treatment, patients were divided into malnutrition group (n = 123) and non-malnutrition group (n = 184). The nutritional status of patients was evaluated according to the Micro-Nutrition Assessment Scale (MNA). Evaluation of indicators was performed, including general information, disease characteristics of PTB-T2DM and laboratory indicators.Results: Univariate logistic regression analysis showed that drinking, divorced, BMI < 18.5kg/m2, weight < 45kg, waist circumference < 79cm, hip circumference < 88cm, waist-to-hip ratio < 69.99, calf circumference < 26kg, grip strength < 28kg, NRS score ≥ 3, Hb < 106g/L, Alb < 29.00g/L, PA < 48.00μmol/L, GHB < 3.40%, serum transferrin < 1.37 mmol/L, serum potassium < 3.18mmol/L, serum sodium < 142.95 mmol/L, FEV1 ≥ 67.90% and RV < 2.89% were risk factors for malnutrition in PTB-T2DM patients (all P < 0.05). The results of multivariate logistic regression analysis showed that drinking, divorced, weight < 45kg, BMI < 18.5kg/m2, NRS score ≥ 3, Hb < 106g/L, Alb < 29.00g/L, PA < 48.00μmol/L, serum transferrin < 1.37mmol/L, FEV1 ≥ 67.90% and RV < 2.89% were independent risk factors for malnutrition in PTB-T2DM patients (all P < 0.05).Conclusion: Drinking, divorced, weight < 45kg, BMI < 18.5kg/m2, NRS score ≥ 3, Hb < 106g/L, Alb < 29.00g/L, PA < 48.00μmol/L, serum transferrin < 1.37mmol/L, FEV1 ≥ 67.90% and RV < 2.89% may be independent risk factors for malnutrition in PTB-T2DM patients, and timely identification of high-risk groups could improve the prognosis of PTB-T2DM patients.Keywords: risk factors, malnutrition, type 2 diabetes mellitus, pulmonary tuberculosis |
| first_indexed | 2024-04-11T05:43:48Z |
| format | Article |
| id | doaj.art-aede9c35f1634973a9f2e1582d8def73 |
| institution | Directory Open Access Journal |
| issn | 1178-6973 |
| language | English |
| last_indexed | 2024-04-11T05:43:48Z |
| publishDate | 2022-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Infection and Drug Resistance |
| spelling | doaj.art-aede9c35f1634973a9f2e1582d8def732022-12-22T04:42:19ZengDove Medical PressInfection and Drug Resistance1178-69732022-12-01Volume 157555756480499Analysis on the Risk Factors of Malnutrition in Type 2 Diabetes Mellitus Patients with Pulmonary TuberculosisMa LChen XGao MLiangliang Ma,1 Xuelin Chen,1 Maolong Gao2 1Department of Infectious Diseases, Beijing Geriatric Hospital, Beijing, 100095, People’s Republic of China; 2Department of Science and Technology, Beijing Geriatric Hospital, Beijing, 100095, People’s Republic of ChinaCorrespondence: Liangliang Ma, Department of Infectious Diseases, Beijing Geriatric Hospital, No. 118 Wenquan Road, Haidian District, Beijing, 100095, People’s Republic of China, Tel +86-18610672953, Email gkdp29@163.comObjective: To explore the risk factors of malnutrition in type 2 diabetes mellitus combined with pulmonary tuberculosis (PTB-T2DM) patients and further to provide a clinical research basis for the identification and prevention of malnutrition.Methods: From January 2020 to February 2022, 307 adult patients diagnosed with PTB-T2DM were enrolled in this retrospective study. According to whether malnutrition occurred after 6 months of treatment, patients were divided into malnutrition group (n = 123) and non-malnutrition group (n = 184). The nutritional status of patients was evaluated according to the Micro-Nutrition Assessment Scale (MNA). Evaluation of indicators was performed, including general information, disease characteristics of PTB-T2DM and laboratory indicators.Results: Univariate logistic regression analysis showed that drinking, divorced, BMI < 18.5kg/m2, weight < 45kg, waist circumference < 79cm, hip circumference < 88cm, waist-to-hip ratio < 69.99, calf circumference < 26kg, grip strength < 28kg, NRS score ≥ 3, Hb < 106g/L, Alb < 29.00g/L, PA < 48.00μmol/L, GHB < 3.40%, serum transferrin < 1.37 mmol/L, serum potassium < 3.18mmol/L, serum sodium < 142.95 mmol/L, FEV1 ≥ 67.90% and RV < 2.89% were risk factors for malnutrition in PTB-T2DM patients (all P < 0.05). The results of multivariate logistic regression analysis showed that drinking, divorced, weight < 45kg, BMI < 18.5kg/m2, NRS score ≥ 3, Hb < 106g/L, Alb < 29.00g/L, PA < 48.00μmol/L, serum transferrin < 1.37mmol/L, FEV1 ≥ 67.90% and RV < 2.89% were independent risk factors for malnutrition in PTB-T2DM patients (all P < 0.05).Conclusion: Drinking, divorced, weight < 45kg, BMI < 18.5kg/m2, NRS score ≥ 3, Hb < 106g/L, Alb < 29.00g/L, PA < 48.00μmol/L, serum transferrin < 1.37mmol/L, FEV1 ≥ 67.90% and RV < 2.89% may be independent risk factors for malnutrition in PTB-T2DM patients, and timely identification of high-risk groups could improve the prognosis of PTB-T2DM patients.Keywords: risk factors, malnutrition, type 2 diabetes mellitus, pulmonary tuberculosishttps://www.dovepress.com/analysis-on-the-risk-factors-of-malnutrition-in-type-2-diabetes-mellit-peer-reviewed-fulltext-article-IDRrisk factorsmalnutritiontype 2 diabetic mellituspulmonary tuberculosis |
| spellingShingle | Ma L Chen X Gao M Analysis on the Risk Factors of Malnutrition in Type 2 Diabetes Mellitus Patients with Pulmonary Tuberculosis Infection and Drug Resistance risk factors malnutrition type 2 diabetic mellitus pulmonary tuberculosis |
| title | Analysis on the Risk Factors of Malnutrition in Type 2 Diabetes Mellitus Patients with Pulmonary Tuberculosis |
| title_full | Analysis on the Risk Factors of Malnutrition in Type 2 Diabetes Mellitus Patients with Pulmonary Tuberculosis |
| title_fullStr | Analysis on the Risk Factors of Malnutrition in Type 2 Diabetes Mellitus Patients with Pulmonary Tuberculosis |
| title_full_unstemmed | Analysis on the Risk Factors of Malnutrition in Type 2 Diabetes Mellitus Patients with Pulmonary Tuberculosis |
| title_short | Analysis on the Risk Factors of Malnutrition in Type 2 Diabetes Mellitus Patients with Pulmonary Tuberculosis |
| title_sort | analysis on the risk factors of malnutrition in type 2 diabetes mellitus patients with pulmonary tuberculosis |
| topic | risk factors malnutrition type 2 diabetic mellitus pulmonary tuberculosis |
| url | https://www.dovepress.com/analysis-on-the-risk-factors-of-malnutrition-in-type-2-diabetes-mellit-peer-reviewed-fulltext-article-IDR |
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