Photodynamic action of the red laser on Propionibacterium acnes
Abstract: Background: Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species. Objective: To evaluate the effect of red laser 660nm with the photosensitizer methylene blue o...
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Format: | Article |
Language: | English |
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Sociedade Brasileira de Dermatologia
2017-10-01
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Series: | Anais Brasileiros de Dermatologia |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500622&tlng=en |
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author | Rogério Rodrigo Ramos Jeferson Leandro de Paiva José Paulo Franco dos Santos Gomes Nagib Pezati Boer José Maria Pereira de Godoy Fernando Batigalia |
author_facet | Rogério Rodrigo Ramos Jeferson Leandro de Paiva José Paulo Franco dos Santos Gomes Nagib Pezati Boer José Maria Pereira de Godoy Fernando Batigalia |
author_sort | Rogério Rodrigo Ramos |
collection | DOAJ |
description | Abstract: Background: Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species. Objective: To evaluate the effect of red laser 660nm with the photosensitizer methylene blue on Propionibacterium acnes in vitro. Method: The experimental design was distributed into four groups (1 - control group without the application of light and without photosensitizer, 2 - application of light, 3 - methylene blue without light, and 4 - methylene blue with light). Tests were subjected to red laser irradiation 660nm by four cycles of 5 minutes at 3-minute intervals. Results: It was evidenced the prominence of the fourth cycle (20 minutes) groups 2, 3 and 4. Study limitations: Despite the favorable results, the laser irradiation time photosensitizer associated with methylene blue were not sufficient to to completely inhibit the proliferation of bacteria. Conclusion: Further studies in vitro are recommended to enable the clinical application of this photosensitizer in photodynamic therapy. |
first_indexed | 2024-04-11T17:22:48Z |
format | Article |
id | doaj.art-aedf8c84a4d4405da9bd078a83b68929 |
institution | Directory Open Access Journal |
issn | 0365-0596 |
language | English |
last_indexed | 2024-04-11T17:22:48Z |
publishDate | 2017-10-01 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | Article |
series | Anais Brasileiros de Dermatologia |
spelling | doaj.art-aedf8c84a4d4405da9bd078a83b689292022-12-22T04:12:27ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962017-10-0192562262510.1590/abd1806-4841.20175651Photodynamic action of the red laser on Propionibacterium acnesRogério Rodrigo RamosJeferson Leandro de PaivaJosé Paulo Franco dos Santos GomesNagib Pezati BoerJosé Maria Pereira de GodoyFernando BatigaliaAbstract: Background: Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species. Objective: To evaluate the effect of red laser 660nm with the photosensitizer methylene blue on Propionibacterium acnes in vitro. Method: The experimental design was distributed into four groups (1 - control group without the application of light and without photosensitizer, 2 - application of light, 3 - methylene blue without light, and 4 - methylene blue with light). Tests were subjected to red laser irradiation 660nm by four cycles of 5 minutes at 3-minute intervals. Results: It was evidenced the prominence of the fourth cycle (20 minutes) groups 2, 3 and 4. Study limitations: Despite the favorable results, the laser irradiation time photosensitizer associated with methylene blue were not sufficient to to completely inhibit the proliferation of bacteria. Conclusion: Further studies in vitro are recommended to enable the clinical application of this photosensitizer in photodynamic therapy.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500622&tlng=enLaser therapyMethylene bluePropionibacterium acnes |
spellingShingle | Rogério Rodrigo Ramos Jeferson Leandro de Paiva José Paulo Franco dos Santos Gomes Nagib Pezati Boer José Maria Pereira de Godoy Fernando Batigalia Photodynamic action of the red laser on Propionibacterium acnes Anais Brasileiros de Dermatologia Laser therapy Methylene blue Propionibacterium acnes |
title | Photodynamic action of the red laser on Propionibacterium acnes |
title_full | Photodynamic action of the red laser on Propionibacterium acnes |
title_fullStr | Photodynamic action of the red laser on Propionibacterium acnes |
title_full_unstemmed | Photodynamic action of the red laser on Propionibacterium acnes |
title_short | Photodynamic action of the red laser on Propionibacterium acnes |
title_sort | photodynamic action of the red laser on propionibacterium acnes |
topic | Laser therapy Methylene blue Propionibacterium acnes |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500622&tlng=en |
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