Photodynamic action of the red laser on Propionibacterium acnes

Abstract: Background: Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species. Objective: To evaluate the effect of red laser 660nm with the photosensitizer methylene blue o...

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Main Authors: Rogério Rodrigo Ramos, Jeferson Leandro de Paiva, José Paulo Franco dos Santos Gomes, Nagib Pezati Boer, José Maria Pereira de Godoy, Fernando Batigalia
Format: Article
Language:English
Published: Sociedade Brasileira de Dermatologia 2017-10-01
Series:Anais Brasileiros de Dermatologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500622&tlng=en
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author Rogério Rodrigo Ramos
Jeferson Leandro de Paiva
José Paulo Franco dos Santos Gomes
Nagib Pezati Boer
José Maria Pereira de Godoy
Fernando Batigalia
author_facet Rogério Rodrigo Ramos
Jeferson Leandro de Paiva
José Paulo Franco dos Santos Gomes
Nagib Pezati Boer
José Maria Pereira de Godoy
Fernando Batigalia
author_sort Rogério Rodrigo Ramos
collection DOAJ
description Abstract: Background: Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species. Objective: To evaluate the effect of red laser 660nm with the photosensitizer methylene blue on Propionibacterium acnes in vitro. Method: The experimental design was distributed into four groups (1 - control group without the application of light and without photosensitizer, 2 - application of light, 3 - methylene blue without light, and 4 - methylene blue with light). Tests were subjected to red laser irradiation 660nm by four cycles of 5 minutes at 3-minute intervals. Results: It was evidenced the prominence of the fourth cycle (20 minutes) groups 2, 3 and 4. Study limitations: Despite the favorable results, the laser irradiation time photosensitizer associated with methylene blue were not sufficient to to completely inhibit the proliferation of bacteria. Conclusion: Further studies in vitro are recommended to enable the clinical application of this photosensitizer in photodynamic therapy.
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spelling doaj.art-aedf8c84a4d4405da9bd078a83b689292022-12-22T04:12:27ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962017-10-0192562262510.1590/abd1806-4841.20175651Photodynamic action of the red laser on Propionibacterium acnesRogério Rodrigo RamosJeferson Leandro de PaivaJosé Paulo Franco dos Santos GomesNagib Pezati BoerJosé Maria Pereira de GodoyFernando BatigaliaAbstract: Background: Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species. Objective: To evaluate the effect of red laser 660nm with the photosensitizer methylene blue on Propionibacterium acnes in vitro. Method: The experimental design was distributed into four groups (1 - control group without the application of light and without photosensitizer, 2 - application of light, 3 - methylene blue without light, and 4 - methylene blue with light). Tests were subjected to red laser irradiation 660nm by four cycles of 5 minutes at 3-minute intervals. Results: It was evidenced the prominence of the fourth cycle (20 minutes) groups 2, 3 and 4. Study limitations: Despite the favorable results, the laser irradiation time photosensitizer associated with methylene blue were not sufficient to to completely inhibit the proliferation of bacteria. Conclusion: Further studies in vitro are recommended to enable the clinical application of this photosensitizer in photodynamic therapy.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500622&tlng=enLaser therapyMethylene bluePropionibacterium acnes
spellingShingle Rogério Rodrigo Ramos
Jeferson Leandro de Paiva
José Paulo Franco dos Santos Gomes
Nagib Pezati Boer
José Maria Pereira de Godoy
Fernando Batigalia
Photodynamic action of the red laser on Propionibacterium acnes
Anais Brasileiros de Dermatologia
Laser therapy
Methylene blue
Propionibacterium acnes
title Photodynamic action of the red laser on Propionibacterium acnes
title_full Photodynamic action of the red laser on Propionibacterium acnes
title_fullStr Photodynamic action of the red laser on Propionibacterium acnes
title_full_unstemmed Photodynamic action of the red laser on Propionibacterium acnes
title_short Photodynamic action of the red laser on Propionibacterium acnes
title_sort photodynamic action of the red laser on propionibacterium acnes
topic Laser therapy
Methylene blue
Propionibacterium acnes
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500622&tlng=en
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AT josepaulofrancodossantosgomes photodynamicactionoftheredlaseronpropionibacteriumacnes
AT nagibpezatiboer photodynamicactionoftheredlaseronpropionibacteriumacnes
AT josemariapereiradegodoy photodynamicactionoftheredlaseronpropionibacteriumacnes
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