Shared and Cell-Type-Specific Gene Expression Patterns Associated With Autism Revealed by Integrative Regularized Non-Negative Matrix Factorization
Human brain-related disorders, such as autism spectrum disorder (ASD), are often characterized by cell heterogeneity, as the cell atlas of brains consists of diverse cell types. There are commonality and specificity in gene expression among different cell types of brains; hence, there may also be co...
Main Authors: | Jinting Guan, Yan Zhuang, Yue Kang, Guoli Ji |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-05-01
|
Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2022.865371/full |
Similar Items
-
Gene Module Analysis Reveals Cell-Type Specificity and Potential Target Genes in Autism’s Pathogenesis
by: Guoli Ji, et al.
Published: (2021-04-01) -
Cell Type-Specific Gene Network-Based Analysis Depicts the Heterogeneity of Autism Spectrum Disorder
by: Jinting Guan, et al.
Published: (2020-03-01) -
An analytical method for the identification of cell type-specific disease gene modules
by: Jinting Guan, et al.
Published: (2021-01-01) -
Cell Type-Specific Predictive Models Perform Prioritization of Genes and Gene Sets Associated With Autism
by: Jinting Guan, et al.
Published: (2021-01-01) -
SRGS: sparse partial least squares-based recursive gene selection for gene regulatory network inference
by: Jinting Guan, et al.
Published: (2022-11-01)