Biocompatibility of Bacterial Cellulose Based Biomaterials
Some bacteria can synthesize cellulose when they are cultivated under adequate conditions. These bacteria produce a mat of cellulose on the top of the culture medium, which is formed by a three-dimensional coherent network of pure cellulose nanofibers. Bacterial cellulose (BC) has been widely used i...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-12-01
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| Series: | Journal of Functional Biomaterials |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2079-4983/3/4/864 |
| _version_ | 1798039069166403584 |
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| author | Omar P. Troncoso Solene Commeaux Fernando G. Torres |
| author_facet | Omar P. Troncoso Solene Commeaux Fernando G. Torres |
| author_sort | Omar P. Troncoso |
| collection | DOAJ |
| description | Some bacteria can synthesize cellulose when they are cultivated under adequate conditions. These bacteria produce a mat of cellulose on the top of the culture medium, which is formed by a three-dimensional coherent network of pure cellulose nanofibers. Bacterial cellulose (BC) has been widely used in different fields, such as the paper industry, electronics and tissue engineering due to its remarkable mechanical properties, conformability and porosity. Nanocomposites based on BC have received much attention, because of the possibility of combining the good properties of BC with other materials for specific applications. BC nanocomposites can be processed either in a static or an agitated medium. The fabrication of BC nanocomposites in static media can be carried out while keeping the original mat structure obtained after the synthesis to form the final nanocomposite or by altering the culture media with other components. The present article reviews the issue of biocompatibility of BC and BC nanocomposites. Biomedical aspects, such as surface modification for improving cell adhesion, in vitro and in vivo studies are given along with details concerning the physics of network formation and the changes that occur in the cellulose networks due to the presence of a second phase. The relevance of biocompatibility studies for the development of BC-based materials in bone, skin and cardiovascular tissue engineering is also discussed. |
| first_indexed | 2024-04-11T21:48:49Z |
| format | Article |
| id | doaj.art-aef0144e88df459bad000a1c1072759a |
| institution | Directory Open Access Journal |
| issn | 2079-4983 |
| language | English |
| last_indexed | 2024-04-11T21:48:49Z |
| publishDate | 2012-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Functional Biomaterials |
| spelling | doaj.art-aef0144e88df459bad000a1c1072759a2022-12-22T04:01:19ZengMDPI AGJournal of Functional Biomaterials2079-49832012-12-013486487810.3390/jfb3040864Biocompatibility of Bacterial Cellulose Based BiomaterialsOmar P. TroncosoSolene CommeauxFernando G. TorresSome bacteria can synthesize cellulose when they are cultivated under adequate conditions. These bacteria produce a mat of cellulose on the top of the culture medium, which is formed by a three-dimensional coherent network of pure cellulose nanofibers. Bacterial cellulose (BC) has been widely used in different fields, such as the paper industry, electronics and tissue engineering due to its remarkable mechanical properties, conformability and porosity. Nanocomposites based on BC have received much attention, because of the possibility of combining the good properties of BC with other materials for specific applications. BC nanocomposites can be processed either in a static or an agitated medium. The fabrication of BC nanocomposites in static media can be carried out while keeping the original mat structure obtained after the synthesis to form the final nanocomposite or by altering the culture media with other components. The present article reviews the issue of biocompatibility of BC and BC nanocomposites. Biomedical aspects, such as surface modification for improving cell adhesion, in vitro and in vivo studies are given along with details concerning the physics of network formation and the changes that occur in the cellulose networks due to the presence of a second phase. The relevance of biocompatibility studies for the development of BC-based materials in bone, skin and cardiovascular tissue engineering is also discussed.http://www.mdpi.com/2079-4983/3/4/864bacterial cellulosebiocompatibilitybiomedical applicationbiomaterials |
| spellingShingle | Omar P. Troncoso Solene Commeaux Fernando G. Torres Biocompatibility of Bacterial Cellulose Based Biomaterials Journal of Functional Biomaterials bacterial cellulose biocompatibility biomedical application biomaterials |
| title | Biocompatibility of Bacterial Cellulose Based Biomaterials |
| title_full | Biocompatibility of Bacterial Cellulose Based Biomaterials |
| title_fullStr | Biocompatibility of Bacterial Cellulose Based Biomaterials |
| title_full_unstemmed | Biocompatibility of Bacterial Cellulose Based Biomaterials |
| title_short | Biocompatibility of Bacterial Cellulose Based Biomaterials |
| title_sort | biocompatibility of bacterial cellulose based biomaterials |
| topic | bacterial cellulose biocompatibility biomedical application biomaterials |
| url | http://www.mdpi.com/2079-4983/3/4/864 |
| work_keys_str_mv | AT omarptroncoso biocompatibilityofbacterialcellulosebasedbiomaterials AT solenecommeaux biocompatibilityofbacterialcellulosebasedbiomaterials AT fernandogtorres biocompatibilityofbacterialcellulosebasedbiomaterials |