Response of pro-inflammatory prostaglandin contents in anti-inflammatory supplements from green mussel Perna viridis L. in a time-dependent accelerated shelf-life study
The effect of natural antioxidant additives on pro-inflammatory prostaglandins, PGE2 and PGF2α vis-à-vis C20n-6 fatty acid in the green mussel, Perna viridis extract (MSL) and those of MSL supplemented with additives (in GMET1 through GMET4) were investigated in an accelerated shelf-life study (50 °...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2014-03-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464614000048 |
| _version_ | 1818937051536424960 |
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| author | Kajal Chakraborty Selsa Jose Chakkalakal Deepu Joseph |
| author_facet | Kajal Chakraborty Selsa Jose Chakkalakal Deepu Joseph |
| author_sort | Kajal Chakraborty |
| collection | DOAJ |
| description | The effect of natural antioxidant additives on pro-inflammatory prostaglandins, PGE2 and PGF2α vis-à-vis C20n-6 fatty acid in the green mussel, Perna viridis extract (MSL) and those of MSL supplemented with additives (in GMET1 through GMET4) were investigated in an accelerated shelf-life study (50 °C) of 90 days. HPLC was employed for quantifying PGE2 and PGF2α and their chemical structures were assigned by signature peaks based on ESI-LC–MS and 1H NMR. The concentrations of PGE2 and PGF2α after an accelerated shelf-life study of 90 days were significantly higher (P < 0.05) in MSL on day 90 of the intervention than among GMET2 and GMET4. An inverse correlation between antioxidative effects of the additives and pro-inflammatory eicosanoids in GMET2 and GMET4 at baseline and at the end of the study was apparent. The results describe the utility of quantifying PGE2 and PGF2α as an index of antioxidant status and lipid peroxidation. |
| first_indexed | 2024-12-20T05:45:49Z |
| format | Article |
| id | doaj.art-aef9f05a519444389939dcb63e4101af |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-12-20T05:45:49Z |
| publishDate | 2014-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-aef9f05a519444389939dcb63e4101af2022-12-21T19:51:20ZengElsevierJournal of Functional Foods1756-46462014-03-017527540Response of pro-inflammatory prostaglandin contents in anti-inflammatory supplements from green mussel Perna viridis L. in a time-dependent accelerated shelf-life studyKajal Chakraborty0Selsa Jose Chakkalakal1Deepu Joseph2Corresponding author. Tel.: +91 484 2394867; fax: +91 484 2394909.; Marine Biotechnology Division, Central Marine Fisheries Research Institute, Ernakulam North P.O., P.B. No. 1603, Cochin 682018, Kerala, IndiaMarine Biotechnology Division, Central Marine Fisheries Research Institute, Ernakulam North P.O., P.B. No. 1603, Cochin 682018, Kerala, IndiaMarine Biotechnology Division, Central Marine Fisheries Research Institute, Ernakulam North P.O., P.B. No. 1603, Cochin 682018, Kerala, IndiaThe effect of natural antioxidant additives on pro-inflammatory prostaglandins, PGE2 and PGF2α vis-à-vis C20n-6 fatty acid in the green mussel, Perna viridis extract (MSL) and those of MSL supplemented with additives (in GMET1 through GMET4) were investigated in an accelerated shelf-life study (50 °C) of 90 days. HPLC was employed for quantifying PGE2 and PGF2α and their chemical structures were assigned by signature peaks based on ESI-LC–MS and 1H NMR. The concentrations of PGE2 and PGF2α after an accelerated shelf-life study of 90 days were significantly higher (P < 0.05) in MSL on day 90 of the intervention than among GMET2 and GMET4. An inverse correlation between antioxidative effects of the additives and pro-inflammatory eicosanoids in GMET2 and GMET4 at baseline and at the end of the study was apparent. The results describe the utility of quantifying PGE2 and PGF2α as an index of antioxidant status and lipid peroxidation.http://www.sciencedirect.com/science/article/pii/S1756464614000048Perna viridisProstaglandinsFatty acid1H NMRAnti-inflammatory |
| spellingShingle | Kajal Chakraborty Selsa Jose Chakkalakal Deepu Joseph Response of pro-inflammatory prostaglandin contents in anti-inflammatory supplements from green mussel Perna viridis L. in a time-dependent accelerated shelf-life study Journal of Functional Foods Perna viridis Prostaglandins Fatty acid 1H NMR Anti-inflammatory |
| title | Response of pro-inflammatory prostaglandin contents in anti-inflammatory supplements from green mussel Perna viridis L. in a time-dependent accelerated shelf-life study |
| title_full | Response of pro-inflammatory prostaglandin contents in anti-inflammatory supplements from green mussel Perna viridis L. in a time-dependent accelerated shelf-life study |
| title_fullStr | Response of pro-inflammatory prostaglandin contents in anti-inflammatory supplements from green mussel Perna viridis L. in a time-dependent accelerated shelf-life study |
| title_full_unstemmed | Response of pro-inflammatory prostaglandin contents in anti-inflammatory supplements from green mussel Perna viridis L. in a time-dependent accelerated shelf-life study |
| title_short | Response of pro-inflammatory prostaglandin contents in anti-inflammatory supplements from green mussel Perna viridis L. in a time-dependent accelerated shelf-life study |
| title_sort | response of pro inflammatory prostaglandin contents in anti inflammatory supplements from green mussel perna viridis l in a time dependent accelerated shelf life study |
| topic | Perna viridis Prostaglandins Fatty acid 1H NMR Anti-inflammatory |
| url | http://www.sciencedirect.com/science/article/pii/S1756464614000048 |
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