Comparison of the cytokine adsorption ability in continuous renal replacement therapy using polyethyleneimine-coated polyacrylonitrile (AN69ST) or polymethylmethacrylate (PMMA) hemofilters: a pilot single-center open-label randomized control trial

Comparison of the cytokine adsorption ability in continuous renal replacement therapy using polyethyleneimine-coated polyacrylonitrile (AN69ST) or polymethylmethacrylate (PMMA) hemofilters: a pilot single-center open-label randomized control trial

Abstract Background Sepsis occurs as a result of dysregulated host response to infection. However, cytokine adsorption therapy may restore the balance of proinflammatory and anti-inflammatory mediator responses in patients with sepsis. This study aimed to determine the cytokine adsorption ability of...

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Main Authors: Yoshihiko Nakamura, Hiroki Hatomoto, Shintaro Yamasaki, Kazuya Yamauchi, Fumiaki Kiyomi, Kota Hoshino, Yasumasa Kawano, Takafumi Nakano, Takehiro Hasegawa, Hiroyasu Ishikura
Format: Article
Language:English
Published: BMC 2023-06-01
Series:European Journal of Medical Research
Subjects:
Sepsis
Cytokine adsorption
Continuous renal replacement therapy
Polyethyleneimine-coated
Polymethylmethacrylate
Online Access:https://doi.org/10.1186/s40001-023-01184-6

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